product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat E-Selectin ELISA Kit
catalog :
MBS9310499
quantity :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9310499
products type :
ELISA Kit
products full name :
Rat E-Selectin ELISA Kit
products short name :
E-Selectin
products name syn :
Rat E-selectin ELISA Kit; Rat E-Selectin
other names :
E-selectin; E-selectin; E-selectin; ELAM-1; OTTHUMP00000032745; OTTHUMP00000032746; OTTHUMP00000032747; OTTHUMP00000032748; OTTHUMP00000032749; endothelial adhesion molecule 1; CD62 antigen-like family member E; endothelial leukocyte adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; selectin E; CD62 antigen-like family member E; Endothelial leukocyte adhesion molecule 1; ELAM-1; Leukocyte-endothelial cell adhesion molecule 2
products gene name :
E-Selectin
other gene names :
SELE; SELE; ELAM; ESEL; CD62E; ELAM1; LECAM2; ELAM1
uniprot entry name :
LYAM2_HUMAN
ncbi gi num :
187960042
ncbi acc num :
NP_000441.2
ncbi gb acc num :
NM_000450.2
uniprot acc num :
P16581
ncbi mol weight :
66,655 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Malaria Pathway 152665!!Malaria Pathway 152657!!Thromboxane A2 Receptor Signaling Pathway 138060
ncbi summary :
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq]
uniprot summary :
Function: Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis. Ref.1. Subunit structure: Interacts with PSGL1/SELPLG and PODXL2 through the sialyl Lewis X epitope. PSGL1 sulfation appears not to be required for this interaction. Ref.9 Ref.12. Subcellular location: Membrane; Single-pass type I membrane protein. Polymorphism: A polymorphism in position 149 is associated with a higher risk of coronary artery disease (CAD). A significantly higher mutation frequency (Arg-149) is observed in patients with angiographically proven severe atherosclerosis compared with an unselected population (Ser-149). Sequence similarities: Belongs to the selectin/LECAM family.Contains 1 C-type lectin domain.Contains 1 EGF-like domain.Contains 6 Sushi (CCP/SCR) domains.
size :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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