catalog number :
MBS9309650
products type :
ELISA Kit
products full name :
Human Hemoglobin Gamma 1 (HBg1) ELISA Kit
products short name :
Hemoglobin Gamma 1 (HBg1)
other names :
hemoglobin subunit gamma-1; Hemoglobin subunit gamma-1; hemoglobin subunit gamma-1; hb F Agamma; gamma globin; A-gamma globin; gamma-1-globin; gamma A hemoglobin; hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin, gamma, regulator of; hemoglobin, gamma A; Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain
products gene name :
HBg1
products gene name syn :
HB-G1; HBGA; HBGR; HSGGL1
other gene names :
HBG1; HBG1; HBGA; HBGR; HSGGL1; PRO2979
uniprot entry name :
HBG1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.625 ug/ml - 20 ug/ml. Sensitivity: 0.1 ug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HBgamma1 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_000550.2
ncbi gb acc num :
NM_000559.2
ncbi mol weight :
16,140 Da
ncbi summary :
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
uniprot summary :
HBG1: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Belongs to the globin family. Protein type: Carrier. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: hemoglobin complex; cytosol. Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity. Biological Process: oxygen transport; blood coagulation. Disease: Fetal Hemoglobin Quantitative Trait Locus 1