catalog number :
MBS9309444
products type :
ELISA Kit
products full name :
Human Trefoil Factor 2 (TFF2) ELISA Kit
products short name :
[Trefoil Factor 2 (TFF2)]
other names :
[trefoil factor 2; Trefoil factor 2; trefoil factor 2; spasmolysin; spasmolytic protein 1; spasmolytic polypeptide; trefoil factor 2; Spasmolysin; Spasmolytic polypeptide]
products gene name :
[TFF2]
products gene name syn :
[SML1; SP; Spasmolytic Protein 1]
other gene names :
[TFF2; TFF2; SP; SML1; SML1; SP]
uniprot entry name :
TFF2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ITF2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005414.1
ncbi gb acc num :
NM_005423.4
ncbi mol weight :
14,284 Da
ncbi summary :
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
uniprot summary :
TFF2: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: extracellular space. Molecular Function: protein binding; CXCR4 chemokine receptor binding. Biological Process: negative regulation of inflammatory response; positive regulation of cell proliferation; digestion; calcium-mediated signaling; negative regulation of macrophage activation; regulation of cell migration
size4 :
10x96-Strip-Wells