ELISA/assay

Human Tubulin Beta 3 (TUBb3) ELISA Kit

MBS9309384

48-Strip-Wells

470 USD

ELISA Kit

Human Tubulin Beta 3 (TUBb3) ELISA Kit

[Tubulin Beta 3 (TUBb3)]

[tubulin beta-3 chain isoform 2; Tubulin beta-3 chain; tubulin beta-3 chain; tubulin beta-III; tubulin beta-4 chain; class III beta-tubulin; fibrosis of extraocular muscles, congenital, 3; tubulin, beta 3 class III; Tubulin beta-4 chain; Tubulin beta-III]

[TUBb3]

[TUBB3; TUBB3; CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A; TUBB4]

TBB3_HUMAN

Human

Store all reagents at 2-8 degree C

Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of TUBB2C (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

308235963

NP_001184110.1

NM_001197181.1

Q13509

50,433 Da

Chaperonin-mediated Protein Folding Pathway (106242); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway (106243); Diurnally Regulated Genes With Circadian Orthologs Pathway (198813); Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway (106245); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gap Junction Pathway (83072); Gap Junction Pathway (483)

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]

TUBB3: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Dimer of alpha and beta chains. Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues. Belongs to the tubulin family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 16q24.3. Cellular Component: microtubule; cell soma; axon; cytoplasm; dendrite; nucleus. Molecular Function: GTPase activity; protein binding; GTP binding; structural constituent of cytoskeleton; peptide binding. Biological Process: protein polymerization; axon guidance; de novo posttranslational protein folding; mitosis; cellular protein metabolic process; protein folding; transmembrane transport; microtubule-based process. Disease: Fibrosis Of Extraocular Muscles, Congenital, 3a, With Or Without Extraocular Involvement; Cortical Dysplasia, Complex, With Other Brain Malformations 1

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095