catalog number :
MBS9309371
products type :
ELISA Kit
products full name :
Human Amelogenin,X-Linked (AMELX) ELISA Kit
products short name :
[Amelogenin,X-Linked (AMELX)]
other names :
[amelogenin, X isoform isoform 2; Amelogenin, X isoform; amelogenin, X isoform; amelogenesis imperfecta 1; amelogenin (amelogenesis imperfecta 1, X-linked); amelogenin (X chromosome, amelogenesis imperfecta 1); amelogenin, X-linked]
products gene name :
[AMELX]
other gene names :
[AMELX; AMELX; AMG; AI1E; AIH1; ALGN; AMGL; AMGX; AMG; AMGX]
uniprot entry name :
AMELX_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of AMELX (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_872622.1
ncbi gb acc num :
NM_182681.1
ncbi mol weight :
21,603 Da
ncbi summary :
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
AMELX: Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel. Defects in AMELX are the cause of amelogenesis imperfecta type 1E (AI1E). A X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small. Belongs to the amelogenin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: Xp22.31-p22.1. Cellular Component: proteinaceous extracellular matrix; cell surface. Molecular Function: identical protein binding; protein binding; growth factor activity; hydroxyapatite binding; structural constituent of tooth enamel. Biological Process: osteoblast differentiation; cell proliferation; biomineral formation; ion homeostasis; positive regulation of collagen biosynthetic process; chondrocyte differentiation; epithelial to mesenchymal transition; cell adhesion; signal transduction; odontogenesis of dentine-containing teeth. Disease: Amelogenesis Imperfecta, Type Ie
size4 :
10x96-Strip-Wells