ELISA/assay

Human Sclerostin Domain Containing Protein 1 (SOSTDC1) ELISA Kit

MBS9308697

48-Strip-Wells

435 USD

ELISA Kit

Human Sclerostin Domain Containing Protein 1 (SOSTDC1) ELISA Kit

Sclerostin Domain Containing Protein 1 (SOSTDC1)

sclerostin domain-containing protein 1; Sclerostin domain-containing protein 1; sclerostin domain-containing protein 1; ectodermal BMP inhibitor; cystine-knot containing secreted protein; uterine sensitization-associated protein-1; sclerostin domain containing 1; Ectodermal BMP inhibitor; Ectodin; Uterine sensitization-associated gene 1 protein

SOSTDC1

Ectodermal BMP inhibitor,USAG1,USAG-1,Uterine sensitization-associated gene 1 protein

SOSTDC1; SOSTDC1; USAG1; CDA019; ECTODIN; USAG1; Ectodin; USAG-1

SOSD1_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml. Assay Type: Sandwich

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SOSTDC1 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

23943785

NP_056279.1

NM_015464.2

Q6X4U4

23,307 Da

BMP Receptor Signaling Pathway (137948)

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]

SOSTDC1: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. Belongs to the sclerostin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7p21.1. Cellular Component: extracellular space. Biological Process: Wnt receptor signaling pathway; hair follicle morphogenesis; pattern specification process; odontogenesis of dentine-containing teeth; negative regulation of BMP signaling pathway; negative regulation of cell fate commitment

48-Strip-Wells

435 USD

96-Strip-Wells

600