catalog number :
MBS9308671
products type :
ELISA Kit
products full name :
Human Laminin Alpha 5 (LAMa5) ELISA Kit
products short name :
Laminin Alpha 5 (LAMa5)
other names :
laminin subunit alpha-5; Laminin subunit alpha-5; laminin subunit alpha-5; laminin alpha-5 chain; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha; laminin, alpha 5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha
products gene name :
LAMa5
products gene name syn :
LAMA5,Laminin subunit alpha-5,Laminin-10 subunit alpha,Laminin-11 subunit alpha,Laminin-15 subunit alpha
other gene names :
LAMA5; LAMA5; KIAA0533; KIAA1907
uniprot entry name :
LAMA5_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LAMA5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005551.3
ncbi gb acc num :
NM_005560.4
ncbi mol weight :
399,737 Da
ncbi pathways :
Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Degradation Of The Extracellular Matrix Pathway (576263); ECM Proteoglycans Pathway (833812); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067)
ncbi summary :
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
uniprot summary :
LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Extracellular matrix. Chromosomal Location of Human Ortholog: 20q13.2-q13.3. Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus. Molecular Function: integrin binding; structural molecule activity. Biological Process: focal adhesion formation; muscle development; extracellular matrix organization and biogenesis; regulation of embryonic development; regulation of cell migration; extracellular matrix disassembly; morphogenesis of embryonic epithelium; hair follicle development; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; integrin-mediated signaling pathway; regulation of cell adhesion; endothelial cell differentiation; cell migration; cytoskeleton organization and biogenesis; cell recognition; regulation of cell proliferation; odontogenesis of dentine-containing teeth; cell proliferation; embryonic development; ureteric bud branching; lung development