Mouse Angiopoietin Like Protein 4 (ANGPTL4) ELISA Kit | MyBioSource MBS9308508 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Angiopoietin Like Protein 4 (ANGPTL4) ELISA Kit

catalog :

MBS9308508

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9308508

products type :

ELISA Kit

products full name :

Mouse Angiopoietin Like Protein 4 (ANGPTL4) ELISA Kit

products short name :

[Angiopoietin Like Protein 4 (ANGPTL4)]

other names :

[angiopoietin-related protein 4 isoform b; Angiopoietin-related protein 4; angiopoietin-related protein 4; fasting-induced adipose factor; PPARG angiopoietin related protein; hepatic angiopoietin-related protein; hepatic fibrinogen/angiopoietin-related protein; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; angiopoietin-like 4; Angiopoietin-like protein 4; Hepatic fibrinogen/angiopoietin-related protein]

products gene name :

[ANGPTL4]

products gene name syn :

[Angiopoietin-related protein 4,Farp,Fasting-induced adipose factor,Fiaf,Hepatic fibrinogen/angiopoietin-related protein,HFARP,Ng27,Secreted]

other gene names :

[ANGPTL4; ANGPTL4; NL2; ARP4; FIAF; HARP; PGAR; HFARP; UNQ171; pp1158; ANGPTL2; ARP4; HFARP; PGAR; HFARP]

uniprot entry name :

ANGL4_HUMAN

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ANGPTL4 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

89264696

ncbi acc num :

NP_001034756.1

ncbi gb acc num :

NM_001039667.2

uniprot acc num :

Q9BY76

ncbi mol weight :

45,214 Da

ncbi pathways :

Developmental Biology Pathway (477129); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); Transcriptional Regulation Of White Adipocyte Differentiation Pathway (205243)

ncbi summary :

This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]

uniprot summary :

ANGPTL4: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation. Protein type: Extracellular matrix; Secreted; Apoptosis; Inhibitor; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: proteinaceous extracellular matrix; extracellular space; extracellular region. Molecular Function: enzyme inhibitor activity; protein binding. Biological Process: positive regulation of angiogenesis; response to hypoxia; negative regulation of lipoprotein lipase activity; angiogenesis; cellular lipid metabolic process; cell differentiation; protein homooligomerization; negative regulation of apoptosis. Disease: Plasma Triglyceride Level Quantitative Trait Locus

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage