catalog number :
MBS9308113
products type :
ELISA Kit
products full name :
Human Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a) ELISA Kit
products short name :
[Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)]
other names :
[calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 2; Calcium/calmodulin-dependent protein kinase type II subunit alpha; calcium/calmodulin-dependent protein kinase type II subunit alpha; CaMK II; alpha-CaMKII; caMK-II subunit alpha; caM kinase II subunit alpha; calcium/calmodulin-dependent protein kinase II alpha]
products gene name :
[CAMK2a]
products gene name syn :
[Calcium/calmodulin-dependent protein kinase type II subunit alpha,CaM kinase II subunit alpha,CAMKA,CaMK-II subunit alpha]
other gene names :
[Camk2a; Camk2a; CaMKII; R74975; mKIAA0968; CaM kinase II subunit alpha]
uniprot entry name :
KCC2A_MOUSE
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Sheep Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of CAMK2A (hereafter termed "analyte") in undiluted original Sheep body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_803126.1
ncbi gb acc num :
NM_177407.4
ncbi mol weight :
54,115 Da
ncbi pathways :
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (926536); Adrenergic Signaling In Cardiomyocytes Pathway (908268); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Amphetamine Addiction Pathway (547634); Amphetamine Addiction Pathway (550546); CREB Phosphorylation Through The Activation Of CaMKII Pathway (926543); CREB Phosphorylation Through The Activation Of Ras Pathway (926539); Ca2+ Pathway (927049); Calcium Regulation In The Cardiac Cell Pathway (198327); Calcium Signaling Pathway (83247)
uniprot summary :
CAMK2A: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.7.11.17; Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CAMK group; CAMK2 family. Cellular Component: dendrite cytoplasm; cell soma; mitochondrion; membrane; axon; cytoplasm; postsynaptic density; dendrite; plasma membrane; synapse; cell junction; nucleus. Molecular Function: glutamate receptor binding; protein homodimerization activity; calmodulin-dependent protein kinase activity; nucleotide binding; GTPase activating protein binding; protein kinase activity; calmodulin binding; transferase activity; protein serine/threonine kinase activity; protein binding; transferase activity, transferring phosphorus-containing groups; kinase activity; ATP binding. Biological Process: peptidyl-serine phosphorylation; ionotropic glutamate receptor signaling pathway; calcium ion transport; protein amino acid autophosphorylation; regulation of neurotransmitter secretion; positive regulation of calcium ion transport; phosphorylation; protein amino acid phosphorylation; regulation of neuronal synaptic plasticity; G1/S transition of mitotic cell cycle; activation of NF-kappaB transcription factor
size4 :
10x96-Strip-Wells