catalog number :
MBS9307839
products type :
ELISA Kit
products full name :
Human Secreted Frizzled Related Protein 4 (SFRP4) ELISA Kit
products short name :
[Secreted Frizzled Related Protein 4 (SFRP4)]
other names :
[secreted frizzled-related protein 4; Secreted frizzled-related protein 4; secreted frizzled-related protein 4; frizzled protein, human endometrium; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; Frizzled protein, human endometrium]
products gene name :
[SFRP4]
products gene name syn :
[Frizzled protein, human endometrium,FrpHE,FRPHE,sFRP-4]
other gene names :
[SFRP4; SFRP4; FRP-4; FRPHE; sFRP-4; FRPHE; sFRP-4; FrpHE]
uniprot entry name :
SFRP4_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SFRP4 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_003005.2
ncbi gb acc num :
NM_003014.3
ncbi mol weight :
39,827 Da
ncbi pathways :
Adipogenesis Pathway (198832); Wnt Signaling Pathway (198789); Wnt Signaling Pathway (83061); Wnt Signaling Pathway (471)
ncbi summary :
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008]
uniprot summary :
SFRP4: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. Belongs to the secreted frizzled-related protein (sFRP) family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 7p14.1. Cellular Component: extracellular space; cell surface; cytoplasm; integral to membrane; nucleus. Molecular Function: G-protein coupled receptor activity; Wnt-protein binding; protein binding; Wnt receptor activity. Biological Process: negative regulation of cell proliferation; positive regulation of apoptosis; negative regulation of transcription factor activity; multicellular organismal development; positive regulation of epidermal cell differentiation; positive regulation of receptor internalization; response to hormone stimulus; phosphate ion homeostasis; cell differentiation
size4 :
10x96-Strip-Wells