Human RAD51 Homolog (RAD51) ELISA Kit | MyBioSource MBS9307320 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human RAD51 Homolog (RAD51) ELISA Kit

catalog :

MBS9307320

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9307320

products type :

ELISA Kit

products full name :

Human RAD51 Homolog (RAD51) ELISA Kit

products short name :

[RAD51 Homolog (RAD51)]

other names :

[RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog 1; RAD51 homolog A; RecA-like protein; recombination protein A; RecA, E. coli, homolog of; BRCA1/BRCA2-containing complex, subunit 5; RAD51 recombinase; RAD51 homolog A]

products gene name :

[RAD51]

products gene name syn :

[DNA repair protein RAD51 homolog 1,hRAD51,HsRAD51,RAD51 homolog A,RAD51A,RECA]

other gene names :

[RAD51; RAD51; RECA; BRCC5; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930; RAD51A; RECA; HsRAD51; hRAD51]

uniprot entry name :

RAD51_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV(%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RAD51 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

49168602

ncbi acc num :

CAG38796.1

uniprot acc num :

Q06609

ncbi mol weight :

36,966 Da

ncbi pathways :

Assembly Of The RAD51-ssDNA Nucleoprotein Complex Pathway (105873); BARD1 Signaling Events Pathway (137959); DNA Repair Pathway (105837); DNA Damage Response Pathway (198788); Double-Strand Break Repair Pathway (105861); Fanconi Anemia Pathway (377262); Fanconi Anemia Pathway (377128); Homologous DNA Pairing And Strand Exchange Pathway (105870); Homologous Recombination Repair Pathway (105862); Homologous Recombination Pathway (198890)

ncbi summary :

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

uniprot summary :

RAD51: a member of the RAD51 protein family. Involved in the homologous recombination and repair of DNA. Interacts with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. Interacts with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both its intracellular localization and DNA-binding ability. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Defects in RAD51 are associated with breast cancer. Two alternatively spliced isoforms have been reported. Protein type: Mitochondrial; DNA repair, damage. Chromosomal Location of Human Ortholog: 15q15.1. Cellular Component: nuclear chromosome; PML body; condensed nuclear chromosome; mitochondrion; condensed chromosome; nucleoplasm; lateral element; mitochondrial matrix; perinuclear region of cytoplasm; cytoplasm; nucleolus; microtubule organizing center; nucleus. Molecular Function: protein C-terminus binding; identical protein binding; protein binding; double-stranded DNA binding; damaged DNA binding; single-stranded DNA binding; ATP binding; single-stranded DNA-dependent ATPase activity. Biological Process: DNA unwinding during replication; meiosis; DNA recombinase assembly; mitotic recombination; meiotic recombination; double-strand break repair; positive regulation of DNA ligation; DNA repair; response to DNA damage stimulus; protein homooligomerization; double-strand break repair via homologous recombination; DNA recombination. Disease: Breast Cancer; Mirror Movements 2

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage