catalog number :
MBS9306518
products type :
ELISA Kit
products full name :
Mouse Protein jagged-2, JAG2 ELISA Kit
products short name :
[Protein jagged-2, JAG2]
other names :
[protein jagged-2 isoform b; Protein jagged-2; protein jagged-2; jagged 2]
products gene name :
[JAG2]
other gene names :
[JAG2; JAG2; HJ2; SER2; Jagged2; hJ2]
uniprot entry name :
JAG2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of JAG2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_660142.1
ncbi gb acc num :
NM_145159.2
ncbi mol weight :
133,367 Da
ncbi pathways :
Activated NOTCH1 Transmits Signal To The Nucleus Pathway (576270); Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway (771591); Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway (771595); Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway (771593); Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway (771589); Delta-Notch Signaling Pathway (198879); Disease Pathway (530764); FBXW7 Mutants And NOTCH1 In Cancer Pathway (771596); NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway (771602); Notch Signaling Pathway (198891)
ncbi summary :
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
JAG2: Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development. Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Cell surface. Chromosomal Location of Human Ortholog: 14q32. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding; growth factor activity; calcium ion binding; Notch binding. Biological Process: regulation of cell adhesion; thymic T cell selection; Notch signaling pathway; in utero embryonic development; Notch receptor processing; cell cycle; regulation of cell migration; odontogenesis of dentine-containing teeth; regulation of cell proliferation; respiratory system process; morphogenesis of embryonic epithelium; spermatogenesis; auditory receptor cell fate commitment; cell differentiation; skeletal development; T cell differentiation; gamma-delta T cell differentiation
size4 :
10x96-Strip-Wells