ELISA/assay

Porcine TGF-beta receptor type-1, TGFBR1 ELISA Kit

MBS9306341

48-Strip-Wells

470 USD

ELISA Kit

Porcine TGF-beta receptor type-1, TGFBR1 ELISA Kit

[TGF-beta receptor type-1, TGFBR1]

[TGF-beta receptor type-1 isoform 1; TGF-beta receptor type-1; TGF-beta receptor type-1; tbetaR-I; TGF-beta receptor type I; TGF-beta type I receptor; activin receptor-like kinase 5; multiple self-healing squamous epithelioma; transforming growth factor beta receptor I; serine/threonine-protein kinase receptor R4; activin A receptor type II-like kinase, 53kD; activin A receptor type II-like kinase, 53kDa; transforming growth factor-beta receptor type I; activin A receptor type II-like protein kinase of 53kD; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD); transforming growth factor, beta receptor 1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transforming growth factor-beta receptor type I]

[TGFBR1]

[TGFBR1; TGFBR1; AAT5; ALK5; ESS1; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4; ALK5; SKR4; TGFR-1; ALK-5; ALK5; SKR4; TGF-beta receptor type I; TbetaR-I]

TGFR1_HUMAN

Porcine

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TGFBR1 (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

4759226

NP_004603.1

NM_004612.2

P36897

55,960 Da

ALK1 Signaling Events Pathway (137968); Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Chronic Myeloid Leukemia Pathway (83116); Chronic Myeloid Leukemia Pathway (528); Colorectal Cancer Pathway (83106); Colorectal Cancer Pathway (518); Cytokine-cytokine Receptor Interaction Pathway (83051)

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

TGFBR1: a TKL kinase of the serine/threonine-protein kinase receptor (STKR) family. R1 and R2 TGF-beta receptors dimerize after binding TGF-beta at the cell surface. Found in all tissues; most abundant in placenta and least abundant in brain and heart. Protein type: EC 2.7.11.30; Protein kinase, TKL; Membrane protein, integral; Receptor, misc.; Protein kinase, Ser/Thr (receptor); Kinase, protein; TKL group; STKR family; Type1 subfamily. Chromosomal Location of Human Ortholog: 9q22. Cellular Component: tight junction; membrane; cell; plasma membrane; receptor complex; endosome. Molecular Function: transforming growth factor beta receptor activity; protein serine/threonine kinase activity; protein binding; transforming growth factor beta receptor activity, type I; transforming growth factor beta binding; metal ion binding; growth factor binding; receptor signaling protein activity; punt binding; SMAD binding; ATP binding; receptor signaling protein serine/threonine kinase activity; protein kinase activity. Biological Process: lens development in camera-type eye; blastocyst development; collagen fibril organization; wound healing; activation of MAPKK activity; regulation of protein ubiquitination; apoptosis; positive regulation of transcription, DNA-dependent; heart development; negative regulation of chondrocyte differentiation; activin receptor signaling pathway; cell motility involved in cell locomotion; palate development; signal transduction; protein amino acid phosphorylation; post-embryonic development; anterior/posterior pattern formation; regulation of transcription, DNA-dependent; extracellular structure organization and biogenesis; transforming growth factor beta receptor signaling pathway; germ cell migration; positive regulation of cell proliferation; angiogenesis; kidney development; cell cycle arrest; skeletal development; positive regulation of filopodium formation; pharyngeal system development; thymus development; in utero embryonic development; male gonad development; neuron fate commitment; peptidyl-threonine phosphorylation; embryonic cranial skeleton morphogenesis; positive regulation of cell motility; positive regulation of cell growth; parathyroid gland development; endothelial cell activation; positive regulation of protein kinase B signaling cascade; peptidyl-serine phosphorylation; mesenchymal cell differentiation; skeletal morphogenesis; regulation of gene expression; regulation of protein binding; negative regulation of endothelial cell proliferation; epithelial to mesenchymal transition; artery morphogenesis; endothelial cell migration; positive regulation of endothelial cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway. Disease: Multiple Self-healing Squamous Epithelioma, Susceptibility To

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095