Bovine Pulmonary surfatcant-associated protein C, SP-C ELISA Kit | MyBioSource MBS9305205 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Bovine Pulmonary surfatcant-associated protein C, SP-C ELISA Kit

catalog :

MBS9305205

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9305205

products type :

ELISA Kit

products full name :

Bovine Pulmonary surfatcant-associated protein C, SP-C ELISA Kit

products short name :

[Pulmonary surfatcant-associated protein C, SP-C]

other names :

[pulmonary surfactant-associated protein C isoform 2 proprotein; Pulmonary surfactant-associated protein C; pulmonary surfactant-associated protein C; SP5; BRICHOS domain containing 6; pulmonary surfactant apoprotein-2 SP-C; pulmonary surfactant-associated proteolipid SPL(Val); surfactant protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SP5]

products gene name :

[SP-C]

other gene names :

[SFTPC; SFTPC; SP-C; PSP-C; SFTP2; SMDP2; BRICD6; SFTP2; SP-C]

uniprot entry name :

PSPC_HUMAN

reactivity :

Bovine

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 3.12 pg/ml - 100 pg/ml. Sensitivity: 1.0 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPC (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

288915543

ncbi acc num :

NP_001165828.1

ncbi gb acc num :

NM_001172357.1

uniprot acc num :

P11686

ncbi mol weight :

21,053 Da

ncbi summary :

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]

uniprot summary :

SFTPC: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2); also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS); also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called hyaline membranes . 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 8p21. Cellular Component: multivesicular body; extracellular space. Molecular Function: protein binding; protein homodimerization activity. Biological Process: circadian rhythm; response to cAMP; response to hyperoxia; response to retinoic acid; response to glucocorticoid stimulus; response to glucose stimulus; response to lipopolysaccharide; respiratory gaseous exchange; protein homooligomerization; response to vitamin A. Disease: Pulmonary Fibrosis, Idiopathic; Surfactant Metabolism Dysfunction, Pulmonary, 2

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095