ELISA/assay

Human CC Chemokine receptor 6, CCR-6 ELISA Kit

MBS9304485

96 Strip Wells

600 USD

ELISA Kit

Human CC Chemokine receptor 6, CCR-6 ELISA Kit

CC Chemokine receptor 6, CCR-6

C-C chemokine receptor type 6; C-C chemokine receptor type 6; C-C chemokine receptor type 6; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupled receptor 29; G-protein coupled receptor 29; seven-transmembrane receptor, lymphocyte, 22; chemokine (C-C motif) receptor 6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor

CCR-6

CCR6; CCR6; BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6; CKRL3; CMKBR6; GPR29; STRL22; C-C CKR-6; CC-CKR-6; CCR-6; CKR-L3; GPRCY4

CCR6_HUMAN

Human

37188165

NP_113597.2

NM_031409.3

P51684

42,494 Da

Beta Defensins Pathway 530759!!Chemokine Receptors Bind Chemokines Pathway 106359!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Defensins Pathway 530757!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

Function: Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. Ref.1. Subcellular location: Cell membrane; Multi-pass membrane protein. Tissue specificity: Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes. Induction: By IL2/interleukin-2. Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Caution: It is uncertain whether Met-1 or Met-6 is the initiator. Sequence caution: The sequence CAB02144.1 differs from that shown. Reason: Erroneous initiation.

96 Strip Wells

600 USD