catalog number :
MBS9304313
products type :
ELISA Kit
products full name :
Human M-Phase Phosphoprotein 8 (MPHOSPH8) ELISA Kit
products short name :
M-Phase Phosphoprotein 8 (MPHOSPH8)
other names :
MPHOSPH8 protein; M-phase phosphoprotein 8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; two hybrid-associated protein 3 with RanBPM; M-phase phosphoprotein 8; Two hybrid-associated protein 3 with RanBPM
products gene name :
MPHOSPH8
other gene names :
MPHOSPH8; MPHOSPH8; TWA3; mpp8; HSMPP8; RP11-523H24.1; MPP8; Twa3
uniprot entry name :
MPP8_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MPHOSPH8 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
AAH46214.1
ncbi mol weight :
97,182 Da
uniprot summary :
MPHOSPH8: Involved in transcriptional regulation. Specifically recognizes and binds methylated Lys-9 of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell cycle regulation. Chromosomal Location of Human Ortholog: 13q12.11. Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleolus; nuclear heterochromatin; nucleus. Molecular Function: protein binding; methylated histone residue binding. Biological Process: transcription, DNA-dependent; negative regulation of transcription, DNA-dependent