product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Atonal Homolog 1 (ATOH1) ELISA Kit
catalog :
MBS9304243
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9304243
products type :
ELISA Kit
products full name :
Human Atonal Homolog 1 (ATOH1) ELISA Kit
products short name :
Atonal Homolog 1 (ATOH1)
other names :
ATOH1 protein; Protein atonal homolog 1; protein atonal homolog 1; helix-loop-helix protein hATH-1; class A basic helix-loop-helix protein 14; atonal homolog 1 (Drosophila); Class A basic helix-loop-helix protein 14; bHLHa14; Helix-loop-helix protein hATH-1
products gene name :
ATOH1
other gene names :
ATOH1; ATOH1; ATH1; HATH1; MATH-1; bHLHa14; ATH1; BHLHA14; bHLHa14; hATH1
uniprot entry name :
ATOH1_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ATOH1 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi gi num :
47480323
ncbi acc num :
AAH69578.1
uniprot acc num :
Q92858
ncbi mol weight :
38,160 Da
ncbi summary :
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq, Jul 2008]
uniprot summary :
ATOH1: a conserved transcription factor that regulates secretory cell differentiation in colonic epithelium. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. May play a role in the differentiation of subsets of neural cells by activating E box- dependent transcription . Efficient DNA binding requires dimerization with another bHLH protein. Loss of ATOH1 expression in the colon of mice initiates colon cancer. ATOH1 has been silenced in most human colon cancers, and reactivation of this gene in cultured human colon cancer cells is anti-proliferative and induces apoptosis. Protein type: DNA-binding; Cell development/differentiation; Transcription factor. Chromosomal Location of Human Ortholog: 4q22. Cellular Component: nucleus. Molecular Function: protein dimerization activity; chromatin DNA binding; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; axon guidance; inner ear morphogenesis; central nervous system development; auditory receptor cell fate determination; neuron migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of auditory receptor cell differentiation; auditory receptor cell fate specification; cerebral cortex development; positive regulation of neuron differentiation; negative regulation of apoptosis
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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