catalog number :
MBS9304160
products type :
ELISA Kit
products full name :
Human Sterol-O-Acyltransferase 1 (SOAT1) ELISA Kit
products short name :
[Sterol-O-Acyltransferase 1 (SOAT1)]
other names :
[sterol O-acyltransferase 1 isoform 3; Sterol O-acyltransferase 1; sterol O-acyltransferase 1; acyl-coenzyme A:cholesterol acyltransferase 1; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; sterol O-acyltransferase 1; Acyl-coenzyme A:cholesterol acyltransferase 1; ACAT-1; Cholesterol acyltransferase 1]
products gene name :
[SOAT1]
other gene names :
[SOAT1; SOAT1; ACAT; SOAT; STAT; ACACT; ACAT1; ACAT-1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT; ACAT-1]
uniprot entry name :
SOAT1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12ng/ml-100ng/ml. Sensitivity: 1.0ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of SNX4 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001239441.1
ncbi gb acc num :
NM_001252512.1
ncbi mol weight :
64,735 Da
ncbi pathways :
Statin Pathway (198852); Steroid Biosynthesis Pathway (82937); Steroid Biosynthesis Pathway (298)
ncbi summary :
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
uniprot summary :
SOAT1: Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily. Protein type: Transferase; Membrane protein, multi-pass; EC 2.3.1.26; Lipid Metabolism - steroid biosynthesis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q25. Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: protein binding; acyl-CoA binding; sterol O-acyltransferase activity; cholesterol binding. Biological Process: cholesterol metabolic process; cholesterol homeostasis; cholesterol efflux; positive regulation of amyloid precursor protein biosynthetic process
size4 :
10x96-Strip-Wells