product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Thymopentin, TP-5 ELISA Kit
catalog :
MBS9303227
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9303227
products type :
ELISA Kit
products full name :
Human Thymopentin, TP-5 ELISA Kit
products short name :
Thymopentin, TP-5
other names :
thymopoietin isoform beta; Lamina-associated polypeptide 2, isoforms beta/gamma; thymopoietin; TP alpha; TP beta/gamma; LEM domain containing 4; lamina-associated polypeptide 2; thymopoietin-related peptide isoform alpha; thymopoietin-related peptide isoforms beta/gamma; thymopoietin; Thymopoietin, isoforms beta/gamma; TP beta/gamma; Thymopoietin-related peptide isoforms beta/gamma; TPRP isoforms beta/gammaCleaved into the following 2 chains:Thymopoietin; TP; Alternative name(s):; SpleninThymopentin; Alternative name(s):; TP5
products gene name :
TP-5
other gene names :
TMPO; TMPO; TP; LAP2; CMD1T; LEMD4; PRO0868; LAP2; TP beta/gamma; TPRP isoforms beta/gamma; TP
uniprot entry name :
LAP2B_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C
ncbi gi num :
73760405
ncbi acc num :
NP_001027454.1
ncbi gb acc num :
NM_001032283.2
uniprot acc num :
P42167
ncbi mol weight :
50,670 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Clearance Of Nuclear Envelope Membranes From Chromatin Pathway (771572); Initiation Of Nuclear Envelope Reformation Pathway (771574); M Phase Pathway (105812); Mitotic Anaphase Pathway (105818); Mitotic Metaphase And Anaphase Pathway (730317); Mitotic Prophase Pathway (105813); Nuclear Envelope Breakdown Pathway (771570); Nuclear Envelope Reassembly Pathway (771573)
ncbi summary :
The protein encoded by this gene resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, May 2010]
uniprot summary :
TMPO: a single-pass type II membrane protein. Tightly associated with the nuclear lamina. Binds DNA and involved in DNA replication and chromatin remodeling, May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with HAP95. Associated with dilated cardiomyopathy; upregulated in medulloblastoma. Used as a pharmaceutical to treat primary and secondary immune deficiencies, autoimmunity, infections and cancer. Available under the names Timunox (Cilag), Sintomodulina (Italofarmaco) and Mepentil (Recordati). Three alternatively spliced isoforms have been described. Protein type: DNA-binding; Membrane protein, integral. Chromosomal Location of Human Ortholog: 12q22. Cellular Component: nuclear membrane; membrane; cytoplasm; integral to membrane; nuclear inner membrane; nuclear envelope; nucleus; chromatin. Molecular Function: protein binding; DNA binding; lamin binding. Biological Process: regulation of transcription, DNA-dependent
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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