catalog number :
MBS9302928
products type :
ELISA Kit
products full name :
Human Kremen protein 1 (KREMEN1) ELISA Kit
products short name :
[Kremen protein 1 (KREMEN1)]
other names :
[kremen protein 1 isoform 3; Kremen protein 1; kremen protein 1; dickkopf receptor; kringle-coding gene marking the eye and the nose; kringle domain-containing transmembrane protein 1; kringle-containing protein marking the eye and the nose; kringle containing transmembrane protein 1; Dickkopf receptor; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose]
products gene name :
[KREMEN1]
other gene names :
[KREMEN1; KREMEN1; KRM1; KREMEN; KREMEN; KRM1]
uniprot entry name :
KREM1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KREMEN1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001034659.2
ncbi gb acc num :
NM_001039570.2
ncbi mol weight :
51,744 Da
ncbi pathways :
Wnt Signaling Network Pathway (137962)
ncbi summary :
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
KREMEN1: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 22q12.1. Cellular Component: membrane; integral to membrane. Molecular Function: protein binding. Biological Process: Wnt receptor signaling pathway; cell communication
size4 :
10x96-Strip-Wells