catalog number :
MBS9302224
products type :
ELISA Kit
products full name :
Human Heat Shock 70kDa Protein 9 (HSPA9) ELISA Kit
products short name :
[Heat Shock 70kDa Protein 9 (HSPA9)]
other names :
[HSPA9 protein; Stress-70 protein, mitochondrial; stress-70 protein, mitochondrial; mortalin-2; p66-mortalin; mortalin, perinuclear; heat shock 70kD protein 9B; peptide-binding protein 74; 75 kDa glucose-regulated protein; heat shock 70kDa protein 9 (mortalin); 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74]
products gene name :
[HSPA9]
other gene names :
[HSPA9; HSPA9; CSA; MOT; MOT2; GRP75; PBP74; GRP-75; HSPA9B; MTHSP75; GRP75; HSPA9B; mt-HSP70; GRP-75; MOT; PBP74]
uniprot entry name :
GRP75_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HSPA9 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAH30634.1
ncbi mol weight :
73,680 Da
ncbi pathways :
Metabolism Of Proteins Pathway (106230); Mitochondrial Protein Import Pathway (576261); Parkin-Ubiquitin Proteasomal System Pathway (700638); RNA Degradation Pathway (117291); RNA Degradation Pathway (116127); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
ncbi summary :
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010]
uniprot summary :
HSPA9B: Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone. Interacts with FXN. Interacts with HSCB. Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2. Belongs to the heat shock protein 70 family. Protein type: Heat shock protein; Nucleolus; Chaperone. Chromosomal Location of Human Ortholog: 5q31.1. Cellular Component: focal adhesion; mitochondrion; cytoplasm; nucleolus. Molecular Function: protein binding; ubiquitin protein ligase binding; unfolded protein binding; ATP binding. Biological Process: cellular protein metabolic process; protein folding; protein export from nucleus; protein targeting to mitochondrion; negative regulation of apoptosis
size4 :
10x96-Strip-Wells