ELISA/assay

Mouse Creatine Kinase, CK ELISA Kit

MBS9301010

48-Strip-Wells

435 USD

ELISA Kit

Mouse Creatine Kinase, CK ELISA Kit

Creatine Kinase, CK

creatine kinase; Creatine kinase U-type, mitochondrial; creatine kinase U-type, mitochondrial; U-MtCK; mia-CK; ubiquitous mitochondrial creatine kinase; acidic-type mitochondrial creatine kinase; creatine kinase, mitochondrial 1 (ubiquitous); creatine kinase, mitochondrial 1B; Acidic-type mitochondrial creatine kinase; Mia-CK; Ubiquitous mitochondrial creatine kinase

CK

CKMT1B; CKMT1A; CKMT; CKMT1; UMTCK; CKMT; Mia-CK; U-MtCK

KCRU_HUMAN

Mouse

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 12.5 U/L - 400 U/L. Sensitivity: 2.0 U/L.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CK (hereafter termed this analyte) in Mouse serum, plasma and tissue homogenate samples.

180590

AAA98744.1

P12532

47,037 Da

Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Creatine Pathway (413359); Creatine Pathway (468234); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Creatine-phosphate Biosynthesis Pathway (545319); Creatine-phosphate Biosynthesis Pathway (138632)

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]

CKMT1A: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. Exists as an octamer composed of four MTCK homodimers. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Amino Acid Metabolism - arginine and proline; EC 2.7.3.2; Kinase, other; Mitochondrial. Chromosomal Location of Human Ortholog: 15q15. Cellular Component: mitochondrion; mitochondrial inner membrane. Molecular Function: creatine kinase activity; ATP binding. Biological Process: phosphorylation; creatine metabolic process

48-Strip-Wells

435 USD

96-Strip-Wells

600