This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Dynactin 3 (DCTN3) ELISA Kit
catalog :
MBS9300778
quantity :
96 Strip Wells
price :
600 USD
product information
catalog number :
MBS9300778
products type :
ELISA Kit
products full name :
Human Dynactin 3 (DCTN3) ELISA Kit
products short name :
Dynactin 3 (DCTN3)
other names :
dynactin subunit 3 isoform 2; Dynactin subunit 3; dynactin subunit 3; p22; dynactin light chain; dynactin 3, isoform 1; dynactin complex subunit 22 kDa subunit; dynactin 3 (p22); Dynactin complex subunit 22 kDa subunit
products gene name :
DCTN3
other gene names :
DCTN3; DCTN3; DCTN22; DCTN-22; DCTN22; p22
uniprot entry name :
DCTN3_HUMAN
reactivity :
Human
ncbi gi num :
13259514
ncbi acc num :
NP_077324.1
ncbi gb acc num :
NM_024348.2
uniprot acc num :
O75935
ncbi mol weight :
21,119 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Centrosome Maturation Pathway 105807!!G2/M Transition Pathway 105801!!Immune System Pathway 106386!!Loss Of Nlp From Mitotic Centrosomes Pathway 105811!!Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway 105810!!MHC Class II Antigen Presentation Pathway 645290!!Mitotic G2-G2/M Phases Pathway 160942
ncbi summary :
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Together with dynein may be involved in spindle assembly and cytokinesis. Ref.1. Subunit structure: Subunit of dynactin, a multiprotein complex associated with dynein. Subcellular location: Cytoplasm. Cytoplasm cytoskeleton centrosome. Chromosome centromere kinetochore. Cytoplasm cytoskeleton spindle. Cleavage furrow. Midbody. Note: Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells. Ref.1. Tissue specificity: Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain. Ref.1. Sequence similarities: Belongs to the dynactin subunit 3 family. Sequence caution: The sequence CAI13144.1 differs from that shown. Reason: Erroneous initiation. The sequence CAI14178.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI14180.1 differs from that shown. Reason: Erroneous initiation.
size :
96 Strip Wells
price :
600 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!