Rat carbonic anhydrase 2, CA-2 ELISA Kit | MyBioSource MBS9300742 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat carbonic anhydrase 2, CA-2 ELISA Kit

catalog :

MBS9300742

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9300742

products type :

ELISA Kit

products full name :

Rat carbonic anhydrase 2, CA-2 ELISA Kit

products short name :

[carbonic anhydrase 2, CA-2]

other names :

[carbonic anhydrase 2; Carbonic anhydrase 2; carbonic anhydrase 2; carbonic anhydrase B; carbonic anhydrase C; carbonic dehydratase; carbonate dehydratase II; carbonic anhydrase II; Carbonate dehydratase II; Carbonic anhydrase C; CAC; Carbonic anhydrase II]

products gene name :

[CA-2]

other gene names :

[CA2; CA2; CAC; CAII; Car2; CA-II; CAC; CA-II]

uniprot entry name :

CAH2_HUMAN

reactivity :

Rat

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 U/L - 100 U/L. Sensitivity: 1.0 U/L.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CA2 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

4557395

ncbi acc num :

NP_000058.1

ncbi gb acc num :

NM_000067.2

uniprot acc num :

P00918

ncbi mol weight :

29,246 Da

ncbi pathways :

Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Collecting Duct Acid Secretion Pathway (147586); Collecting Duct Acid Secretion Pathway (147560); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Metabolism Pathway (477135); O2/CO2 Exchange In Erythrocytes Pathway (645346); Pancreatic Secretion Pathway (169306); Pancreatic Secretion Pathway (169295)

ncbi summary :

CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. [provided by RefSeq, Jul 2008]

uniprot summary :

CA2: Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Interacts with SLC4A4. Interaction with SLC4A7 regulates SLC4A7 transporter activity. Activated by X-ray, histamine, L-adrenaline, L- and D-phenylalanine, L- and D-histidine, L-His-OMe and beta-Ala- His (carnosine). Competitively inhibited by saccharin, thioxolone, coumarins, 667-coumate, celecoxib (Celebrex), valdecoxib (Bextra), SC-125, SC-560, diclofenac, acetate, azide, bromide, sulfonamide derivatives such as acetazolamide (AZA), methazolamide (MZA), ethoxzolamide (EZA), dichlorophenamide (DCP), brinzolamide, dansylamide, thiabendazole-5-sulfonamide, trifluoromethane sulfonamide and N-hydroxysulfamide, fructose-based sugar sulfamate RWJ-37497, and Foscarnet (phosphonoformate trisodium salt). Repressed strongly by hydrogen sulfide(HS) and weakly by nitrate (NO(3)). Esterase activity weakly reduced by cyanamide. N- hydroxyurea interfers with zinc binding and inhibit activity. Belongs to the alpha-carbonic anhydrase family. Protein type: Energy Metabolism - nitrogen; Lyase; EC 4.2.1.1. Chromosomal Location of Human Ortholog: 8q22. Cellular Component: extracellular space; microvillus; axon; basolateral plasma membrane; apical part of cell; cytoplasm; plasma membrane; cytosol; myelin sheath. Molecular Function: protein binding; carbonate dehydratase activity; zinc ion binding. Biological Process: secretion; positive regulation of osteoclast differentiation; positive regulation of synaptic transmission, GABAergic; positive regulation of cellular pH reduction; one-carbon compound metabolic process; odontogenesis of dentine-containing teeth; response to estrogen stimulus; response to zinc ion; bicarbonate transport; regulation of intracellular pH; positive regulation of bone resorption; morphogenesis of an epithelium; kidney development; response to pH. Disease: Osteopetrosis, Autosomal Recessive 3

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095