Rat Toll-like receptor 9, TLR-9 ELISA Kit | MyBioSource MBS9300320 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat Toll-like receptor 9, TLR-9 ELISA Kit

catalog :

MBS9300320

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9300320

products type :

ELISA Kit

products full name :

Rat Toll-like receptor 9, TLR-9 ELISA Kit

products short name :

[Toll-like receptor 9, TLR-9]

other names :

[toll-like receptor 9; Toll-like receptor 9; toll-like receptor 9; toll-like receptor 9]

products gene name :

[TLR-9]

other gene names :

[Tlr9; Tlr9]

uniprot entry name :

TLR9_MOUSE

reactivity :

Rat

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Sandwich (Quantitative). Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TLR9 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

157057166

ncbi acc num :

NP_112455.2

ncbi gb acc num :

NM_031178.2

uniprot acc num :

Q9EQU3

ncbi mol weight :

116,412 Da

ncbi pathways :

African Trypanosomiasis Pathway (194387); African Trypanosomiasis Pathway (194323); Chagas Disease (American Trypanosomiasis) Pathway (147810); Chagas Disease (American Trypanosomiasis) Pathway (147795); Herpes Simplex Infection Pathway (377874); Herpes Simplex Infection Pathway (377865); IGF1R Signaling Cascade Pathway (819897); IRS-mediated Signalling Pathway (819747); IRS-related Events Pathway (819745); IRS-related Events Triggered By IGF1R Pathway (819899)

uniprot summary :

TLR9: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. Interacts with MYD88 via their respective TIR domains. Interacts (via transmembrane domain) with UNC93B1. Interacts with CD300LH; the interaction may promote full activation of TLR9-triggered innate responses. Interacts with BTK. Interacts with CNPY3 and HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum. Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver. Belongs to the Toll-like receptor family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, misc. Cellular Component: membrane; endoplasmic reticulum; lysosome; basolateral plasma membrane; apical plasma membrane; cytoplasm; plasma membrane; integral to membrane; cytoplasmic vesicle; endosome. Molecular Function: protein binding; siRNA binding; interleukin-1 receptor binding; transmembrane receptor activity; unmethylated CpG binding. Biological Process: positive regulation of JNK activity; regulation of cytokine secretion; positive regulation of interleukin-12 production; maintenance of gastrointestinal epithelium; microglial cell activation; positive regulation of interferon-alpha biosynthetic process; regulation of B cell activation; positive regulation of NF-kappaB import into nucleus; defense response to Gram-negative bacterium; signal transduction; positive regulation of interleukin-18 production; positive regulation of interleukin-10 production; activation of NF-kappaB transcription factor; positive regulation of interleukin-8 production; response to molecule of bacterial origin; negative regulation of interleukin-8 production; positive regulation of interferon-beta production; negative regulation of interleukin-6 production; inflammatory response; defense response to virus; positive regulation of autophagy; regulation of protein amino acid phosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; immune system process; response to virus; positive regulation of interleukin-6 production; positive regulation of tumor necrosis factor production; positive regulation of chemokine production; positive regulation of toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; inhibition of NF-kappaB transcription factor; regulation of inflammatory response; positive regulation of interferon-beta biosynthetic process; toll-like receptor signaling pathway; negative regulation of toll-like receptor signaling pathway; innate immune response; immune response; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; I-kappaB phosphorylation; positive regulation of interferon-gamma biosynthetic process; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of inflammatory response

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095