catalog number :
MBS9300263
products type :
ELISA Kit
products full name :
Human Cochlin (COCH) ELISA Kit
products short name :
[Cochlin (COCH)]
other names :
[cochlin; Cochlin; cochlin; coagulation factor C homolog (Limulus polyphemus); COCH-5B2]
products gene name :
[COCH]
other gene names :
[Coch; Coch; AW122937; Coch-5B2; D12H14S564E]
uniprot entry name :
COCH_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of COCH (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001185764.1
ncbi gb acc num :
NM_001198835.1
ncbi mol weight :
59,950 Da
uniprot summary :
COCH: Plays a role in the control of cell shape and motility in the trabecular meshwork. Defects in COCH are the cause of deafness autosomal dominant type 9 (DFNA9). DFNA9 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA9 is characterized by onset in the fourth or fifth decade of life and initially involves the high frequencies. Deafness is progressive and usually complete by the sixth decade. In addition to cochlear involvement, DFNA9 patients also exhibit a spectrum of vestibular dysfunctions. Penetrance of the vestibular symptoms is often incomplete, and some patients are minimally affected, whereas others suffer from severe balance disturbances and episodes of vertigo. Affected individuals have mucopolysaccharide depositions in the channels of the cochlear and vestibular nerves. These depositions apparently cause strangulation and degeneration of dendritic fibers. Protein type: Secreted, signal peptide; Extracellular matrix; Secreted. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region. Molecular Function: collagen binding; protein binding. Biological Process: regulation of cell shape; sensory perception of sound; defense response to bacterium; positive regulation of innate immune response
size4 :
10x96-Strip-Wells