Human Low molecular weight phosphotyrosine protein phosphatase, ACP1 ELISA Kit | MyBioSource MBS929801 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Low molecular weight phosphotyrosine protein phosphatase, ACP1 ELISA Kit

catalog :

MBS929801

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS929801

products type :

ELISA Kit

products full name :

Human Low molecular weight phosphotyrosine protein phosphatase, ACP1 ELISA Kit

products short name :

[acid phosphatase 1, soluble]

products name syn :

[Human Low molecular weight phosphotyrosine protein phosphatase (ACP1) ELISA kit; HAAP; MGC111030; MGC3499; acid phosphatase of erythrocyte; adipocyte acid phosphatase; cytoplasmic phosphotyrosyl protein phosphatase; low molecular weight phosphotyrosine protein phosphatase; protein t; acid phosphatase 1; soluble]

other names :

[low molecular weight phosphotyrosine protein phosphatase isoform d; Low molecular weight phosphotyrosine protein phosphatase; low molecular weight phosphotyrosine protein phosphatase; LMW-PTP; LMW-PTPase; adipocyte acid phosphatase; red cell acid phosphatase 1; protein tyrosine phosphatase; acid phosphatase of erythrocyte; cytoplasmic phosphotyrosyl protein phosphatase; low molecular weight cytosolic acid phosphatase; acid phosphatase 1, soluble; Adipocyte acid phosphatase; Low molecular weight cytosolic acid phosphatase (EC:3.1.3.2); Red cell acid phosphatase 1]

products gene name :

[ACP1]

other gene names :

[ACP1; ACP1; HAAP; LMW-PTP; LMW-PTPase]

uniprot entry name :

PPAC_HUMAN

reactivity :

Human

sequence length :

158

specificity :

This assay has high sensitivity and excellent specificity for detection of human ACP1. No significant cross-reactivity or interference between human ACP1 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.312 mU/ml -20 mU/ml. Sensitivity: Typically less than 0.078 mU/ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ACP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ACP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ACP1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ACP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

96304457

ncbi acc num :

NP_001035739.1

ncbi gb acc num :

NM_001040649.2

uniprot acc num :

P24666

ncbi mol weight :

18,042 Da

ncbi pathways :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); EPHA2 Forward Signaling Pathway (137961); PDGFR-beta Signaling Pathway (138071); Riboflavin Metabolism Pathway (83012); Riboflavin Metabolism Pathway (398); T Cell Receptor Signaling Pathway (198862)

ncbi summary :

The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]

uniprot summary :

ACP1: a phosphotyrosine protein phosphatase. Functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. Hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. Genetically polymorphic with three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene. Protein type: Motility/polarity/chemotaxis; Cofactor and Vitamin Metabolism - riboflavin; Phosphatase (non-protein); EC 3.1.3.2; Protein phosphatase, tyrosine (non-receptor); EC 3.1.3.48. Chromosomal Location of Human Ortholog: 2p25. Cellular Component: internal side of plasma membrane; cytoplasm. Molecular Function: protein binding; acid phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

495

size3 :

96-Strip-Wells

price3 :

710

size4 :

5x96-Strip-Wells

price4 :

2705

size5 :

10x96-Strip-Wells

price5 :

5145

more info or order :

MyBioSource product webpage