Human C-C motif chemokine 16, CCL16 ELISA Kit | MyBioSource MBS929753 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human C-C motif chemokine 16, CCL16 ELISA Kit

catalog :

MBS929753

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

product information

catalog number :

MBS929753

products type :

ELISA Kit

products full name :

Human C-C motif chemokine 16, CCL16 ELISA Kit

products short name :

[chemokine (C-C motif) ligand 16]

products name syn :

[Human C-C motif chemokine 16 (CCL16) ELISA kit; CKb12; HCC-4; ILINCK; LCC-1; LEC; LMC; MGC117051; Mtn-1; NCC-4; NCC4; SCYA16; SCYL4; IL-10-inducible chemokine; chemokine CC-4; chemokine LEC; liver CC chemokine-1; liver-expressed chemokine; lymphocyte; chemokine (C-C motif) ligand 16]

other names :

[C-C motif chemokine 16; C-C motif chemokine 16; C-C motif chemokine 16; monotactin-1; chemokine LEC; chemokine CC-4; new CC chemokine 4; liver CC chemokine-1; IL-10-inducible chemokine; liver-expressed chemokine; small-inducible cytokine A16; lymphocyte and monocyte chemoattractant; small inducible cytokine subfamily A (Cys-Cys), member 16; chemokine (C-C motif) ligand 16; Chemokine CC-4; HCC-4; Chemokine LEC; IL-10-inducible chemokine; LCC-1; Liver-expressed chemokine; Lymphocyte and monocyte chemoattractant; LMC; Monotactin-1; MTN-1; NCC-4; Small-inducible cytokine A16]

products gene name :

[CCL16]

other gene names :

[CCL16; CCL16; LEC; LMC; NCC4; CKb12; HCC-4; LCC-1; Mtn-1; NCC-4; SCYL4; ILINCK; SCYA16; ILINCK; NCC4; SCYA16; HCC-4; LMC; MTN-1]

uniprot entry name :

CCL16_HUMAN

reactivity :

Human

sequence length :

120

specificity :

This assay has high sensitivity and excellent specificity for detection of human CCL16. No significant cross-reactivity or interference between human CCL16 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 39.06 pg/ml-2500 pg/ml. Sensitivity: Typically less than 9.77 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CCL16 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CCL16 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CCL16 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CCL16 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

4759074

ncbi acc num :

NP_004581.1

ncbi gb acc num :

NM_004590.2

uniprot acc num :

O15467

ncbi mol weight :

13,600 Da

ncbi pathways :

Chemokine Receptors Bind Chemokines Pathway (106359); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Peptide Ligand-binding Receptors Pathway (106358)

ncbi summary :

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]

uniprot summary :

CCL16: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Belongs to the intercrine beta (chemokine CC) family. Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine; Secreted. Chromosomal Location of Human Ortholog: 17q12. Cellular Component: extracellular space; extracellular region. Molecular Function: chemokine activity; chemoattractant activity. Biological Process: cell-cell signaling; positive chemotaxis; immune response; cell communication; chemotaxis; inflammatory response

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

495

size3 :

96-Strip-Wells

price3 :

710

size4 :

5x96-Strip-Wells

price4 :

2705

size5 :

10x96-Strip-Wells

price5 :

5145