Human SPARC-related modular calcium-binding protein 2, SMOC2 ELISA Kit | MyBioSource MBS928218 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human SPARC-related modular calcium-binding protein 2, SMOC2 ELISA Kit

catalog :

MBS928218

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS928218

products type :

ELISA Kit

products full name :

Human SPARC-related modular calcium-binding protein 2, SMOC2 ELISA Kit

products short name :

SPARC related modular calcium binding 2

products name syn :

Human SPARC-related modular calcium-binding protein 2 (SMOC2) ELISA kit; RP11-270C4__A.1; MST117; MSTP117; MSTP140; SMAP2; bA270C4A.1; bA37D8.1; dJ421D16.1; secreted modular calcium-binding protein 2; smooth muscle associated protein 2; thyroglobulin type-1 repeat containi; SPARC related modular calcium binding 2

other names :

SPARC-related modular calcium-binding protein 2 isoform 2; SPARC-related modular calcium-binding protein 2; SPARC-related modular calcium-binding protein 2; SMAP-2; SMOC-2; smooth muscle associated protein 2; smooth muscle-associated protein 2; secreted modular calcium-binding protein 2; thyroglobulin type-1 repeat containing protein; SPARC related modular calcium binding 2; Secreted modular calcium-binding protein 2; SMOC-2; Smooth muscle-associated protein 2; SMAP-2

products gene name :

SMOC2

other gene names :

SMOC2; SMOC2; DTDP1; SMAP2; MST117; MSTP117; MSTP140; bA37D8.1; bA270C4A.1; dJ421D16.1; SMAP2; MSTP117; SMOC-2; SMAP-2

uniprot entry name :

SMOC2_HUMAN

reactivity :

Human

sequence length :

446

specificity :

This assay has high sensitivity and excellent specificity for detection of human SMOC2. No significant cross-reactivity or interference between human SMOC2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates, cell culture superantes. Assay Type: Sandwich. Detection Range: 0.156 ng/ml -10 ng/ml. Sensitivity: 0.039 ng /ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SMOC2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SMOC2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SMOC2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SMOC2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

262050673

ncbi acc num :

NP_001159884.1

ncbi gb acc num :

NM_001166412.1

uniprot acc num :

Q9H3U7

ncbi mol weight :

49,674 Da

ncbi summary :

This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

uniprot summary :

SMOC2: Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. Defects in SMOC2 are the cause of dentin dysplasia typ1 (DTDP1). A dental defect in which both primary and secondary dentitions are affected. The clinical crowns of both permanent and deciduous teeth are of normal shape, form and color in most cases, although they may be slightly opalescent and blue or brown. Teeth may be very mobile and exfoliate spontaneously because of inadequate root formation. On radiographs, the roots are short and may be more pointed than normal. Pulp chambers are usually absent except for a chevron-shaped remnant in the crown. Root canals are usually absent. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Calcium-binding; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6q27. Cellular Component: basement membrane. Molecular Function: heparin binding; calcium ion binding. Biological Process: extracellular matrix organization and biogenesis; signal transduction. Disease: Dentin Dysplasia, Type I

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage