Mouse Glia-derived nexin, SERPINE2 ELISA Kit | MyBioSource MBS928069 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Glia-derived nexin, SERPINE2 ELISA Kit

catalog :

MBS928069

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS928069

products type :

ELISA Kit

products full name :

Mouse Glia-derived nexin, SERPINE2 ELISA Kit

products short name :

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1) , member 2

products name syn :

Mouse Glia-derived nexin (SERPINE2) ELISA kit; GDN; PI7; PN1; PNI; OTTHUMP00000203766; glial-derived neurite promoting factor; glial-derived nexin 1; plasminogen activator inhibitor type 1; member 2; protease inhibitor 7 (protease nexin I) ; serine (o; serpin peptidase inhibitor; clade E (nexin; plasminogen activator inhibitor type 1); member 2

other names :

glia-derived nexin; Glia-derived nexin; glia-derived nexin; GDN; serpin E2; protease nexin 1; protease nexin I; peptidase inhibitor 7; serine protease inhibitor 4; serine protease-inhibitor 4; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) peptidase inhibitor, clade E, member 2; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serine protease-inhibitor 4; Serpin E2

products gene name :

SERPINE2

other gene names :

Serpine2; Serpine2; PI7; PI-7; PN-1; Spi4; PAI-1; B230326M24Rik; Pi7; Pn1; Spi4; GDN; PI-7; PN-1

uniprot entry name :

GDN_MOUSE

reactivity :

Mouse

sequence length :

397

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse SERPINE2. No significant cross-reactivity or interference between Mouse SERPINE2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 3.12 pg/ml-200 pg/ml. Sensitivity: 0.78 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Developmental Protein. Protein Biological Process 3: Differentiation

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SERPINE2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SERPINE2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SERPINE2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SERPINE2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

6678099

ncbi acc num :

NP_033281.1

ncbi gb acc num :

NM_009255.4

uniprot acc num :

Q07235

ncbi mol weight :

44,207 Da

uniprot summary :

SERPINE2: Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Inhibitor; Secreted, signal peptide. Cellular Component: extracellular matrix; extracellular space; extrinsic to external side of plasma membrane; membrane; cell soma; cell; extracellular region; cytosol; neuromuscular junction; vesicle. Molecular Function: serine-type endopeptidase inhibitor activity; heparin binding; glycosaminoglycan binding; protease inhibitor activity; receptor binding. Biological Process: negative regulation of proteolysis; nervous system development; regulation of synaptic transmission, glutamatergic; secretory granule organization and biogenesis; multicellular organismal development; cerebellar granular layer morphogenesis; negative regulation of peptidase activity; negative regulation of blood coagulation; mating plug formation; detection of mechanical stimulus involved in sensory perception; negative regulation of cell proliferation; negative regulation of smoothened signaling pathway; response to wounding; negative regulation of cell growth; blood coagulation; cell differentiation; negative regulation of protein catabolic process; regulation of timing of cell differentiation; negative regulation of phosphoinositide 3-kinase cascade; positive regulation of astrocyte differentiation; secretion by cell

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage