Human Glycoprotein hormones alpha chain, CGA ELISA Kit | MyBioSource MBS928045 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Glycoprotein hormones alpha chain, CGA ELISA Kit

catalog :

MBS928045

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

product information

catalog number :

MBS928045

products type :

ELISA Kit

products full name :

Human Glycoprotein hormones alpha chain, CGA ELISA Kit

products short name :

[glycoprotein hormones, alpha polypeptide]

products name syn :

[Human Glycoprotein hormones alpha chain (CGA) ELISA kit; CG-ALPHA; FSHA; GPHA1; GPHa; HCG; LHA; TSHA; chorionic gonadotropin; alpha polypeptide; follicle-stimulating hormone alpha subunit; glycoprotein hormones; alpha polypeptide]

other names :

[glycoprotein hormones alpha chain isoform 2; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain]

products gene name :

[CGA]

other gene names :

[CGA; CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha]

uniprot entry name :

GLHA_HUMAN

reactivity :

Human

sequence length :

116

specificity :

This assay has high sensitivity and excellent specificity for detection of human CGA. No significant cross-reactivity or interference between human CGA and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, plasma, urine, cell culture supernates, tissue homogenates. Assay Type: Sandwich. Detection Range: 4 mIU/ml -12 0 mIU/ml. Sensitivity: 1 mIU/ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CGA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for CGA. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CGA bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

4502787

ncbi acc num :

NP_000726.1

ncbi gb acc num :

NM_000735.3

uniprot acc num :

P01215

ncbi mol weight :

13,075 Da

ncbi pathways :

Amine-derived Hormones Pathway (160983); Androgen Biosynthesis Pathway (106154); Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Glucocorticoid Receptor Regulatory Network Pathway (138014); Glycoprotein Hormones Pathway (160989)

ncbi summary :

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

uniprot summary :

CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q12-q21. Cellular Component: extracellular region. Molecular Function: protein binding; hormone activity. Biological Process: cellular protein metabolic process; cell-cell signaling; positive regulation of cell proliferation; peptide hormone processing; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

435

size3 :

96-Strip-Wells

price3 :

625

size4 :

5x96-Strip-Wells

price4 :

2595

size5 :

10x96-Strip-Wells

price5 :

4905