Human Lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1 ELISA Kit | MyBioSource MBS926647 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1 ELISA Kit

catalog :

MBS926647

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS926647

products type :

ELISA Kit

products full name :

Human Lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1 ELISA Kit

products short name :

[lymphatic vessel endothelial hyaluronan receptor 1]

products name syn :

[Human Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1) ELISA kit; CRSBP-1; HAR; LYVE-1; XLKD1; cell surface retention sequence binding protein-1; extracellular link domain containing 1; extracellular link domain-containing 1; hyaluronic acid receptor; lymphatic vessel endothelial hyaluronan receptor 1]

other names :

[lymphatic vessel endothelial hyaluronic acid receptor 1; Lymphatic vessel endothelial hyaluronic acid receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; lymphatic vessel endothelial hyaluronan receptor 1; Cell surface retention sequence-binding protein 1; CRSBP-1; Extracellular link domain-containing protein 1; Hyaluronic acid receptor]

products gene name :

[LYVE1]

other gene names :

[LYVE1; LYVE1; HAR; XLKD1; LYVE-1; CRSBP-1; CRSBP1; HAR; XLKD1; UNQ230/PRO263; LYVE-1; CRSBP-1]

uniprot entry name :

LYVE1_HUMAN

reactivity :

Human

sequence length :

322

specificity :

This assay has high sensitivity and excellent specificity for detection of human LYVE1. No significant cross-reactivity or interference between human LYVE1 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 19.5 pg/ml-1250 pg/ml. Sensitivity: 4.88 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LYVE1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LYVE1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LYVE1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LYVE1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

40549451

ncbi acc num :

NP_006682.2

ncbi gb acc num :

NM_006691.3

uniprot acc num :

Q9Y5Y7

ncbi mol weight :

35,213 Da

ncbi pathways :

Glycosaminoglycan Metabolism Pathway (645297); Hyaluronan Metabolism Pathway (645298); Hyaluronan Uptake And Degradation Pathway (645300); Metabolism Pathway (477135); Metabolism Of Carbohydrates Pathway (106196)

ncbi summary :

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]

uniprot summary :

XLKD1: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 11p15. Cellular Component: membrane; integral to plasma membrane; plasma membrane. Molecular Function: transmembrane receptor activity; hyaluronic acid binding; receptor activity. Biological Process: anatomical structure morphogenesis; glycosaminoglycan metabolic process; transport; cell-matrix adhesion; carbohydrate metabolic process; response to wounding; pathogenesis; signal transduction; cell motility; hyaluronan metabolic process; hyaluronan catabolic process

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

435

size3 :

96-Strip-Wells

price3 :

625

size4 :

5x96-Strip-Wells

price4 :

2595

size5 :

10x96-Strip-Wells

price5 :

4905

more info or order :

MyBioSource product webpage