Mouse Transforming growth factor beta receptor type 3, TGFBR3 ELISA Kit | MyBioSource MBS926500 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Transforming growth factor beta receptor type 3, TGFBR3 ELISA Kit

catalog :

MBS926500

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS926500

products type :

ELISA Kit

products full name :

Mouse Transforming growth factor beta receptor type 3, TGFBR3 ELISA Kit

products short name :

transforming growth factor, beta receptor III

products name syn :

Mouse Transforming growth factor beta receptor type 3 (TGFBR3) ELISA kit; BGCAN; betaglycan; betaglycan proteoglycan; transforming growth factor; beta receptor III

other names :

transforming growth factor beta receptor type 3; Transforming growth factor beta receptor type 3; transforming growth factor beta receptor type 3; TGFR-3; betaglycan; TGF-beta receptor type 3; TGF-beta receptor type III; transforming growth factor, beta receptor III; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III

products gene name :

TGFBR3

other gene names :

Tgfbr3; Tgfbr3; TBRIII; AU015626; AW215636; 1110036H20Rik; TGF-beta receptor type 3; TGFR-3; TGF-beta receptor type III

uniprot entry name :

TGBR3_MOUSE

reactivity :

Mouse

sequence length :

850

specificity :

This assay has high sensitivity and excellent specificity for detection of mouse TGFBR3. No significant cross-reactivity or interference between mouse TGFBR3 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 6.25 pg/ml -400 pg/ml. Sensitivity: The minimum detectable dose of mouse TGFBR3 is typically less than 1.56 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TGFBR3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TGFBR3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TGFBR3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TGFBR3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

47271511

ncbi acc num :

NP_035708.2

ncbi gb acc num :

NM_011578.3

uniprot acc num :

O88393

ncbi mol weight :

93,829 Da

ncbi pathways :

TGF Beta Signaling Pathway (198393); TGF-beta Receptor Signaling Pathway (198330)

uniprot summary :

TGFBR3: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Interacts with TCTEX1D4. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Cellular Component: proteinaceous extracellular matrix; extracellular space; cell surface; membrane; endoplasmic reticulum; integral to plasma membrane; cytoplasm; extracellular region; integral to membrane; plasma membrane; receptor complex; external side of plasma membrane. Molecular Function: heparin binding; transforming growth factor beta receptor activity; protein binding; fibroblast growth factor binding; glycosaminoglycan binding; transforming growth factor beta binding; punt binding; activin binding; coreceptor activity; SMAD binding; transforming growth factor beta receptor binding; PDZ domain binding. Biological Process: transforming growth factor beta receptor complex assembly; blood vessel development; blastocyst development; in utero embryonic development; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of cell motility; cardiac muscle cell proliferation; palate development; liver development; protein amino acid phosphorylation; activation of NF-kappaB transcription factor; BMP signaling pathway; embryonic development; regulation of protein binding; transforming growth factor beta receptor signaling pathway; epithelial to mesenchymal transition; ventricular cardiac muscle morphogenesis; immune response; protein complex assembly; cell growth; regulation of blood vessel size; negative regulation of transforming growth factor beta receptor signaling pathway; response to follicle-stimulating hormone stimulus; negative regulation of epithelial cell proliferation

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage