catalog number :
MBS926452
products type :
ELISA Kit
products full name :
Rat complement factor D (adipsin) , CFD ELISA Kit
products short name :
complement factor D (adipsin) (CFD) ELISA kit
products name syn :
Rat complement factor D (adipsin) (CFD) ELISA kit; ADIPSIN; ADN; DF; PFD; C3 convertase activator; D component of complement (adipsin) ; complement factor D; complement factor D preproprotein; properdin factor D; complement factor D (adipsin) (CFD) ELISA kit
other names :
complement factor D; Complement factor D; complement factor D; adipsin; properdin factor D; C3 convertase activator; endogenous vascular elastase; D component of complement (adipsin); complement factor D (adipsin); Adipsin; C3 convertase activator; Endogenous vascular elastase; Properdin factor D
products gene name :
adipsin
other gene names :
Cfd; Cfd; Df; Adn; EVE; Adn; Df
uniprot entry name :
CFAD_RAT
specificity :
This assay has high sensitivity and excellent specificity for detection of Rat adipsin. No significant cross-reactivity or interference between Rat adipsin and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm
other info2 :
Sample Volume: 50-100ul. Protein Biological Process 1: Complement. Protein Biological Process 3: Complement alternate pathway
ncbi acc num :
NP_001071110.1
ncbi gb acc num :
NM_001077642.1
ncbi mol weight :
28,442 Da
ncbi pathways :
Adipogenesis Pathway 198479!!Complement And Coagulation Cascades Pathway 198461!!Complement And Coagulation Cascades Pathway 83465!!Complement And Coagulation Cascades Pathway 484!!Hemostasis Pathway 573899!!Platelet Activation, Signaling And Aggregation Pathway 573909!!Platelet Degranulation Pathway 573926!!Response To Elevated Platelet Cytosolic Ca2+ Pathway 573924!!Staphylococcus Aureus Infection Pathway 172815!!Staphylococcus Aureus Infection Pathway 171867
ncbi summary :
serine protease adipocyte-specific protein mediated by the Notch/Hes-1 signaling pathway; can be used as a fecal biomarker for abnormal intestinal epithelial differentiation [RGD, Feb 2006]
uniprot summary :
Function: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Catalytic activity: Selective cleavage of Arg- -Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.