Mouse Integrin alpha-L, ITGAL ELISA Kit | MyBioSource MBS926344 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Integrin alpha-L, ITGAL ELISA Kit

catalog :

MBS926344

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS926344

products type :

ELISA Kit

products full name :

Mouse Integrin alpha-L, ITGAL ELISA Kit

products short name :

integrin, alpha L (antigen CD11A (p180) , lymphocyte function-associated antigen 1; alpha polypeptide)

products name syn :

Mouse Integrin alpha-L (ITGAL) ELISA kit; CD11A; LFA-1; LFA1A; LFA-1 alpha; antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide; integrin alpha L; integrin gene promoter; lymphocyte function-associated antigen 1; integrin; alpha L (antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide)

other names :

Integrin alpha-L; Integrin alpha-L; integrin alpha-L; alpha L integrin; lymphocyte antigen 15; CD11 antigen-like family member A; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; lymphocyte function associated antigen 1, alpha polypeptide; integrin alpha L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; Lymphocyte antigen 15; Ly-15; CD_antigen: CD11a

products gene name :

ITGAL

other gene names :

Itgal; Itgal; Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A; Lfa-1; Ly-15; LFA-1A; Ly-15

uniprot entry name :

ITAL_MOUSE

reactivity :

Mouse

sequence length :

1163

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse ITGAL. No significant cross-reactivity or interference between Mouse ITGAL and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 23.44 pg/ml-1500 pg/ml. Sensitivity: 5.86 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Cell Adhesion. Protein Biological Process 3: Cell adhesion

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ITGAL has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ITGAL present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ITGAL is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ITGAL bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

341940846

ncbi acc num :

P24063.2

uniprot acc num :

P24063

ncbi mol weight :

128,328 Da

ncbi pathways :

Adaptive Immune System Pathway (575096); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (575507); Epstein-Barr Virus Infection Pathway (585576); Epstein-Barr Virus Infection Pathway (587115); Focal Adhesion Pathway (198353); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); Hemostasis Pathway (575479)

uniprot summary :

ITGAL: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Belongs to the integrin alpha chain family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Cell surface; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis. Cellular Component: cell surface; membrane; integral to membrane; immunological synapse; intercellular junction; integrin complex; external side of plasma membrane. Molecular Function: protein heterodimerization activity; metal ion binding; protein complex binding; ICAM-3 receptor activity; cell adhesion molecule binding. Biological Process: integrin-mediated signaling pathway; cell-matrix adhesion; activated T cell proliferation; positive regulation of calcium-mediated signaling; signal transduction; receptor clustering; heterophilic cell adhesion; leukocyte adhesion; cell-cell adhesion; regulation of cell-cell adhesion; cell surface receptor linked signal transduction; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of cell-cell adhesion; positive regulation of T cell proliferation; cell adhesion

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage