protein

TGFB3 Blocking Peptide (Center)

MBS9230356

0.1 mg

155 USD

Blocking Peptide

TGFB3 Blocking Peptide (Center)

[TGFB3]

[Transforming growth factor beta-3; TGF-beta-3; Latency-associated peptide; LAP; TGFB3]

[Transforming growth factor beta-3; Transforming growth factor beta-3; transforming growth factor beta-3; transforming growth factor beta 3]

[TGFB3]

[TGFB3; TGFB3; ARVD; LDS5; RNHF; ARVD1; TGF-beta3; TGF-beta-3; LAP]

TGFB3_HUMAN

412

The synthetic peptide sequence is selected from aa 235-249 of HUMAN TGFB3

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Function: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. Cellular Location: Latency-associated peptide: Secreted, extracellular space, extracellular matrix {ECO:0000250 UniProtKB:P01137}

Involved in embryogenesis and cell differentiation.

135684

P10600.1

P10600

35,708 Da

AGE-RAGE Signaling Pathway In Diabetic Complications (1319988); AGE-RAGE Signaling Pathway In Diabetic Complications (1319775); ALK1 Signaling Events Pathway (137968); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Chronic Myeloid Leukemia Pathway (83116)

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Mar 2009]

TGFB3: Involved in embryogenesis and cell differentiation. Homodimer; disulfide-linked. Interacts with ASPN. Belongs to the TGF-beta family. Protein type: Ligand, receptor tyrosine kinase; Motility/polarity/chemotaxis; Secreted; Cell development/differentiation; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 14q24. Cellular Component: extracellular matrix; extracellular region; extracellular space; plasma membrane. Molecular Function: cytokine activity; identical protein binding; protein binding; punt binding; transforming growth factor beta binding. Biological Process: alveolus development; in utero embryonic development; intercellular junction assembly and maintenance; mammary gland development; negative regulation of cell proliferation; negative regulation of DNA replication; negative regulation of neuron apoptosis; palate development; platelet degranulation; positive regulation of apoptosis; positive regulation of bone mineralization; positive regulation of collagen biosynthetic process; positive regulation of DNA replication; positive regulation of filopodium formation; positive regulation of protein secretion; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of cell proliferation; regulation of MAPKKK cascade; response to hypoxia; response to progesterone stimulus; salivary gland morphogenesis; transforming growth factor beta receptor signaling pathway; uterine wall breakdown. Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 1; Rienhoff Syndrome

0.1 mg

155 USD