product summary
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company name :
MyBioSource
product type :
protein
product name :
LINGO1 Antibody (N-term) Blocking Peptide
catalog :
MBS9226756
quantity :
0.1 mg
price :
155 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9226756
products type :
Blocking Peptide
products full name :
LINGO1 Antibody (N-term) Blocking Peptide
products short name :
[LINGO1]
products name syn :
[Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A; LINGO1; LERN1; LRRN6A]
other names :
[Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat and Ig domain containing 1; Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A]
products gene name :
[LINGO1]
products gene name syn :
[LERN1; LRRN6A]
other gene names :
[LINGO1; LINGO1; LERN1; LRRN6A; UNQ201; LERN1; LRRN6A]
uniprot entry name :
LIGO1_HUMAN
sequence length :
620
form :
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
storage stability :
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
other info1 :
Cellular Location: Cell membrane; Single-pass type I membrane protein
other info2 :
Tissue Location: Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients
products description :
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).
ncbi gi num :
74760819
ncbi acc num :
Q96FE5.2
uniprot acc num :
Q96FE5
ncbi mol weight :
69,146 Da
ncbi pathways :
Axonal Growth Inhibition (RHOA Activation) Pathway (1269458); BDNF Signaling Pathway (712093); Signal Transduction Pathway (1269379); Signalling By NGF Pathway (1269443); P75 NTR Receptor-mediated Signalling Pathway (1269445); P75NTR Regulates Axonogenesis Pathway (1269456)
uniprot summary :
LINGO1: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 15q24.3. Cellular Component: plasma membrane. Molecular Function: epidermal growth factor receptor binding; protein binding. Biological Process: axonogenesis; negative regulation of axonogenesis; signal transduction
size1 :
0.1 mg
price1 :
155 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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