protein

PGLYRP4 Antibody (Center) Blocking Peptide

MBS9223515

0.1 mg

155 USD

Blocking Peptide

PGLYRP4 Antibody (Center) Blocking Peptide

[PGLYRP4]

[Peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta; PGLYRP4; PGRPIB]

[Peptidoglycan recognition protein 4; Peptidoglycan recognition protein 4; peptidoglycan recognition protein 4; peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta]

[PGLYRP4]

[PGRPIB]

[PGLYRP4; PGLYRP4; PGRPIB; SBBI67; PGRP-Ibeta; PGLYRPIbeta; PGRPIB; PGLYRPIbeta; PGRP-I-beta]

PGRP4_HUMAN

[110811165]

373

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20 degree C.

Cellular Location: Secreted.

Tissue Location: Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.

Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity.

143811439

Q96LB8.2

Q96LB8

Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]

PGLYRP4: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q21. Molecular Function: peptidoglycan binding; peptidoglycan receptor activity. Biological Process: defense response to Gram-positive bacterium; detection of bacterium

0.1 mg

155 USD