catalog number :
MBS922348
products type :
ELISA Kit
products full name :
Human Receptor-type tyrosine-protein phosphatase zeta, PTPRZ1 ELISA Kit
products short name :
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
products name syn :
Human Receptor-type tyrosine-protein phosphatase zeta (PTPRZ1) ELISA kit; HPTPZ; HPTPzeta; PTP-ZETA; PTP18; PTPRZ; PTPZ; RPTPB; RPTPbeta; phosphacan; protein tyrosine phosphatase; receptor-type; zeta polypeptide 1; protein tyrosine phosphatase; receptor-type; zeta1; recepto; protein tyrosine phosphatase; receptor-type; Z polypeptide 1
other names :
receptor-type tyrosine-protein phosphatase zeta isoform 2; Receptor-type tyrosine-protein phosphatase zeta; receptor-type tyrosine-protein phosphatase zeta; receptor-type tyrosine phosphatase beta/zeta; protein-tyrosine phosphatase receptor type Z polypeptide 2; protein tyrosine phosphatase, receptor-type, zeta polypeptide 1; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2
products gene name :
PTPRZ1
other gene names :
PTPRZ1; PTPRZ1; PTPZ; HPTPZ; PTP18; PTPRZ; RPTPB; HPTPzeta; PTP-ZETA; RPTPbeta; phosphacan; R-PTP-zeta-2; HTPZP2; PTPRZ; PTPRZ2; PTPZ; R-PTP-zeta
uniprot entry name :
PTPRZ_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human PTPRZ1. No significant cross-reactivity or interference between human PTPRZ1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 93. 75 pg/ml -6000 pg/ml. Sensitivity: The minimum detectable dose of human PTPRZ1 is typically less than 23.43 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Princple of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PTPRZ1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PTPRZ1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PTPRZ1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PTPRZ1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001193767.1
ncbi gb acc num :
NM_001206838.1
ncbi mol weight :
254,587 Da
ncbi pathways :
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (83102); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (515)
ncbi summary :
This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
uniprot summary :
PTPRZ1: May be involved in the regulation of specific developmental processes in the CNS. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.1.3.48; Receptor protein phosphatase, tyrosine; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 7q31.3. Cellular Component: proteinaceous extracellular matrix; integral to plasma membrane. Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity. Biological Process: learning and/or memory; central nervous system development; axonogenesis; oligodendrocyte differentiation; hemopoietic progenitor cell differentiation; protein amino acid dephosphorylation. Disease: Helicobacter Pylori Infection, Susceptibility To
size4 :
10x96-Strip-Wells