Human 14-3-3 protein eta, YWHAH ELISA Kit | MyBioSource MBS922335 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human 14-3-3 protein eta, YWHAH ELISA Kit

catalog :

MBS922335

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS922335

products type :

ELISA Kit

products full name :

Human 14-3-3 protein eta, YWHAH ELISA Kit

products short name :

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

products name syn :

Human 14-3-3 protein eta (YWHAH) ELISA kit; LL22NC03-44A4.1; YWHA1; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta polypeptide

other names :

14-3-3 protein eta; 14-3-3 protein eta; 14-3-3 protein eta; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; Protein AS1

products gene name :

YWHAH

other gene names :

YWHAH; YWHAH; YWHA1; YWHA1

uniprot entry name :

1433F_HUMAN

reactivity :

Human

sequence length :

246

specificity :

This assay has high sensitivity and excellent specificity for detection of human YWHAH. No significant cross-reactivity or interference between human YWHAH and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.625 ng/ml -40 ng/ml. Sensitivity: 0.156 ng /ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for YWHAH has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any YWHAH present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for YWHAH is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of YWHAH bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

4507951

ncbi acc num :

NP_003396.1

ncbi gb acc num :

NM_003405.3

uniprot acc num :

Q04917

ncbi mol weight :

28,219 Da

ncbi pathways :

Alpha6-Beta4 Integrin Signaling Pathway (198807); Androgen Receptor Signaling Pathway (198806); Calcium Regulation In The Cardiac Cell Pathway (198906); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); Class I PI3K Signaling Events Mediated By Akt Pathway (138020); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); ErbB1 Downstream Signaling Pathway (138057); FoxO Family Signaling Pathway (138036)

ncbi summary :

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]

uniprot summary :

14-3-3 eta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Protein type: Nuclear receptor co-regulator; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 22q12.3. Cellular Component: cytoplasmic vesicle membrane; cytoplasm; plasma membrane; cytosol. Molecular Function: protein domain specific binding; insulin-like growth factor receptor binding; protein binding; enzyme binding; sodium channel regulator activity; protein heterodimerization activity; actin binding; glucocorticoid receptor binding. Biological Process: intracellular protein transport; substantia nigra development; regulation of neuron differentiation; apoptosis; glucocorticoid receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of synaptic plasticity; glucocorticoid catabolic process; negative regulation of dendrite morphogenesis; regulation of sodium ion transport

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage