catalog number :
MBS9219125
products type :
Blocking Peptide
products full name :
RNH1 Antibody (C-term) Blocking peptide
products short name :
[RNH1]
products name syn :
[Ribonuclease inhibitor; Placental ribonuclease inhibitor; Placental RNase inhibitor; Ribonuclease/angiogenin inhibitor 1; RAI; RNH1; PRI; RNH]
other names :
[Ribonuclease inhibitor; Ribonuclease inhibitor; ribonuclease inhibitor; ribonuclease/angiogenin inhibitor 1; Placental ribonuclease inhibitor; Placental RNase inhibitor; Ribonuclease/angiogenin inhibitor 1; RAI]
products gene name :
[RNH1]
products gene name syn :
[PRI; RNH]
other gene names :
[RNH1; RNH1; RAI; RNH; PRI; RNH; Placental RNase inhibitor; RAI]
uniprot entry name :
RINI_HUMAN
form :
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
other info1 :
Cellular Location: Cytoplasm.
products description :
Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.
ncbi mol weight :
49,973 Da
ncbi summary :
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]
uniprot summary :
RNH1: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. Protein type: Inhibitor. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: angiogenin-PRI complex; cytoplasm; nucleoplasm. Molecular Function: protein binding; ribonuclease inhibitor activity. Biological Process: regulation of angiogenesis