product summary
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company name :
MyBioSource
product type :
antibody
product name :
LAF4 Antibody (C-term)
catalog :
MBS9217019
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA
more info or order :
image
image 1 :
Anti-LAF4 Antibody (C-term) at 1:2000 dilution + mouse spleen lysate. Lysates/proteins at 20 ug per lane. Secondary. Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 133 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
image 2 :
The anti-LAF4 Pab is used in Western blot to detect LAF4 in placenta tissue lysate.
product information
catalog number :
MBS9217019
products type :
Antibody
products full name :
LAF4 Antibody (C-term)
products short name :
[LAF4]
products name syn :
[Purified Rabbit Polyclonal Antibody (Pab); AF4/FMR2 family member 3; Lymphoid nuclear protein related to AF4; Protein LAF-4; AFF3; LAF4]
other names :
[AF4/FMR2 family member 3 isoform 2; AF4/FMR2 family member 3; AF4/FMR2 family member 3; AF4/FMR2 family member 3; Lymphoid nuclear protein related to AF4; Protein LAF-4]
products gene name :
[AFF3]
other gene names :
[AFF3; AFF3; LAF4; MLLT2-like; LAF4; Protein LAF-4]
uniprot entry name :
AFF3_HUMAN
clonality :
Polyclonal
isotype :
Ig
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
1251
specificity :
This LAF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1197-1227 amino acids from the C-terminal region of human LAF4 .
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles .
tested application :
WB, E
app notes :
WB~~1:1000
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
other info1 :
Calculated MW: 133476. Antigen Region: 1197-1227
other info2 :
Function: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double- stranded DNA. Cellular Location: Nucleus. Tissue Location: Preferentially expressed in lymphoid tissues, highest levels being found in the thymus.
products description :
Lymphoid nuclear protein related to AF4 (LAF4) is related to MLLT2 which is also referred to as AF4. LAF4 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of LAF4 has defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis.
products references :
Hiwatari, M., et al., Oncogene 22(18):2851-2855 (2003). von Bergh, A.R., et al., Genes Chromosomes Cancer 35(1):92-96 (2002). Liao, X., et al., Mamm. Genome 7(6):467-468 (1996). Ma, C., et al., Blood 87(2):734-745 (1996).
ncbi gi num :
68348716
ncbi acc num :
NP_001020279.1
ncbi gb acc num :
NM_001025108.1
uniprot acc num :
P51826
ncbi summary :
This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
AFF3: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double- stranded DNA. Belongs to the AF4 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor. Chromosomal Location of Human Ortholog: 2q11.2-q12. Cellular Component: cytoplasm; nucleoplasm; nucleus. Molecular Function: double-stranded DNA binding. Biological Process: embryonic hindlimb morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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