catalog number :
MBS9216561
products full name :
ERVK-7 Antibody (N-Term)
products short name :
[ERVK-7]
products name syn :
[Purified Rabbit Polyclonal Antibody (Pab); Endogenous retrovirus group K member 7 Env polyprotein; Envelope polyprotein; HERV-K(III) envelope protein; HERV-K102 envelope protein; HERV-K_1q22 provirus ancestral Env polyprotein; Surface protein; SU; Transmembrane protein; TM, ERVK-7]
other names :
[Endogenous retrovirus group K member 7 Env polyprotein; Endogenous retrovirus group K member 7 Env polyprotein; Envelope polyprotein; HERV-K(III) envelope protein; HERV-K102 envelope protein; HERV-K_1q22 provirus ancestral Env polyprotein]
products gene name :
[ERVK-7]
other gene names :
[ERVK-7; SU; TM]
uniprot entry name :
ENK7_HUMAN
specificity :
This ERVK-7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 96-128 amino acids from human ERVK-7.
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA, IHC-P
app notes :
WB~~:1000-1:2000. IHC-P~~1:25
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Western Blot (WB)
other info1 :
Cellular Location: Virion. Tissue Location: Expressed in lung, placenta, testis, and peripheral blood lymphocytes. Clone Names: RB53926
other info2 :
. Function: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity). Cellular Location: Virion. Tissue Location: Expressed in lung, placenta, testis and peripheral blood lymphocytes.
products categories :
Crown Antibodies; Cell Biology; Microbiology
products description :
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity).
products references :
Barbulescu M.,et al.Curr. Biol. 9:861-868(1999). Sugimoto J.,et al.Genomics 72:137-144(2001). Wang-Johanning F.,et al.Oncogene 22:1528-1535(2003).
ncbi summary :
HERV-K102: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Belongs to the beta type-B retroviral envelope protein family. HERV class-II K(HML-2) env subfamily. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q22
uniprot summary :
HERV-K102: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Belongs to the beta type-B retroviral envelope protein family. HERV class-II K(HML-2) env subfamily. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q22