catalog number :
MBS9216483
products full name :
TST Antibody (C-Term)
products short name :
[TST]
products name syn :
[Purified Rabbit Polyclonal Antibody (Pab); Thiosulfate sulfurtransferase; Rhodanese; TST]
other names :
[thiosulfate sulfurtransferase; Thiosulfate sulfurtransferase; thiosulfate sulfurtransferase; thiosulfate sulfurtransferase (rhodanese); Rhodanese]
products gene name :
[TST]
other gene names :
[TST; TST; RDS]
uniprot entry name :
THTR_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
This TST antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 208-232 amino acids from the human TST.
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
other info1 :
Cellular Location: Mitochondrion Matrix.
other info2 :
Clone Names: RB53290
products categories :
Crown Antibodies; Metabolism; Signal Transduction
products description :
Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.
products references :
Aita N.,et al.Biochem. Biophys. Res. Commun. 231:56-60(1997). Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004). Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Dunham I.,et al.Nature 402:489-495(1999).
ncbi acc num :
NP_001257412.1
ncbi gb acc num :
NM_001270483.1
ncbi pathways :
Cysteine And Methionine Metabolism Pathway (104488); Cysteine And Methionine Metabolism Pathway (103421); Degradation Of Cysteine And Homocysteine Pathway (1270183); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Amino Acids And Derivatives Pathway (1270158); Sulfide Oxidation To Sulfate Pathway (1270184); Sulfur Amino Acid Metabolism Pathway (1270181); Sulfur Metabolism Pathway (83026); Sulfur Metabolism Pathway (417)
ncbi summary :
This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
uniprot summary :
TST: Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity. Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA. Protein type: Mitochondrial; Transferase; EC 2.8.1.1. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: extracellular space; mitochondrion; mitochondrial matrix; mitochondrial inner membrane. Molecular Function: thiosulfate sulfurtransferase activity; 5S rRNA binding. Biological Process: cyanate catabolic process; epithelial cell differentiation; rRNA transport; sulfur amino acid metabolic process; sulfur amino acid catabolic process