product summary
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company name :
MyBioSource
product type :
antibody
product name :
VSIG4 Antibody (C-term)
catalog :
MBS9215155
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9215155 image 1
VSIG4 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the VSIG4 antibody detected the VSIG4 protein (arrow).
product information
catalog number :
MBS9215155
products type :
Antibody
products full name :
VSIG4 Antibody (C-term)
products short name :
[VSIG4]
products name syn :
[V-set and immunoglobulin domain-containing protein 4; Protein Z39Ig; VSIG4; CRIg; Z39IG]
other names :
[V-set and immunoglobulin domain-containing protein 4 isoform 2; V-set and immunoglobulin domain-containing protein 4; V-set and immunoglobulin domain-containing protein 4; V-set and immunoglobulin domain containing 4; Protein Z39Ig]
products gene name :
[VSIG4]
other gene names :
[VSIG4; VSIG4; CRIg; Z39IG; CRIg; Z39IG]
uniprot entry name :
VSIG4_HUMAN
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Human
sequence positions :
[308-335]
sequence length :
305
specificity :
This VSIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the C-terminal region of human VSIG4.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB~~1:1000
image1 heading :
Western Blot (WB)
other info1 :
Function: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
other info2 :
Cellular Location: Membrane; Single-pass type I membrane protein. Tissue Location: Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta Expressed in resting macrophages.
products categories :
Immunology
products description :
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
products references :
Guo, S., et al. Clin. Immunol. 136(2):282-291(2010). Van Loo, P., et al. Haematologica 95(3):440-448(2010). Xu, S., et al. Immunol. Lett. 128(1):46-50(2010). He, J.Q., et al. Mol. Immunol. 45(16):4041-4047(2008). Vogt, L., et al. J. Clin. Invest. 116(10):2817-2826(2006)
ncbi gi num :
154426280
ncbi acc num :
NP_001093901.1
ncbi gb acc num :
NM_001100431.1
uniprot acc num :
Q9Y279
ncbi mol weight :
43987
ncbi summary :
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
uniprot summary :
VSIG4: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: Xq12-q13.3. Cellular Component: integral to membrane. Molecular Function: protein binding. Biological Process: negative regulation of T cell proliferation; complement activation, alternative pathway; negative regulation of interleukin-2 production
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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