product summary
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company name :
MyBioSource
product type :
antibody
product name :
ANP32E Antibody (N-term)
catalog :
MBS9214243
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Fluorescent image of SH-SY5Y cells stained with ANP32E Antibody (N-term). MBS9214243 was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor 555 conjugated with Phalloidin (red).
image 2 :
Western blot analysis of lysates from SH-SY5Y,U-937 cell line and mouse brain tissue lysate(from left to right), using ANP32E Antibody(N-term) (MBS9214243). AP20559a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was.
product information
catalog number :
MBS9214243
products type :
Antibody
products full name :
ANP32E Antibody (N-term)
products short name :
[ANP32E]
products name syn :
[Acidic leucine-rich nuclear phosphoprotein 32 family member E; LANP-like protein; LANP-L; ANP32E]
other names :
[acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 2; Acidic leucine-rich nuclear phosphoprotein 32 family member E; acidic leucine-rich nuclear phosphoprotein 32 family member E; acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; LANP-like protein; LANP-L]
products gene name :
[ANP32E]
other gene names :
[ANP32E; ANP32E; LANPL; LANP-L; LANP-L]
uniprot entry name :
AN32E_HUMAN
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Human, mouse (Predicted Reactivity: Rat)
sequence length :
220
specificity :
This ANP32E antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-44 amino acids from the N-terminal region of human ANP32E.
purity :
Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA), Immunofluorescence (IF)
app notes :
IF~~1:25. WB~~1:1000
image1 heading :
Immunofluorescence (IF)
image2 heading :
Western Blot (WB)
other info1 :
Calculated MW: 30692
other info2 :
Function: Histone chaperone that specifically mediates the genome- wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis. Cellular location : Cytoplasm. Nucleus. Tissue location : Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney.
products categories :
Crown Antibodies; Cell Biology; Metabolism; Neuroscience; Signal Transduction
products description :
Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity).
products references :
Jiang M.,et al.Cytogenet. Genome Res. 97:68-71(2002). Ota T.,et al.Nat. Genet. 36:40-45(2004). Bechtel S.,et al.BMC Genomics 8:399-399(2007). Gregory S.G.,et al.Nature 441:315-321(2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
ncbi gi num :
210147569
ncbi acc num :
NP_001129950.1
ncbi gb acc num :
NM_001136478.3
uniprot acc num :
Q9BTT0
uniprot summary :
LANP-L: Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity. Belongs to the ANP32 family. Protein type: Protein phosphatase, regulatory subunit; Inhibitor; Motility/polarity/chemotaxis; Vesicle. Chromosomal Location of Human Ortholog: 1q21.2. Cellular Component: cytoplasmic membrane-bound vesicle; nucleus. Molecular Function: phosphatase inhibitor activity; histone binding. Biological Process: negative regulation of catalytic activity; histone exchange
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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