RPL3 Antibody (Center) | MyBioSource MBS9214187 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

RPL3 Antibody (Center)

catalog :

MBS9214187

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

[RB33092]

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

RPL3 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the RPL3 antibody detected the RPL3 protein (arrow).

image 2 :

RPL3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RPL3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

product information

catalog number :

MBS9214187

products type :

Antibody

products full name :

RPL3 Antibody (Center)

products short name :

[RPL3]

products name syn :

[60S ribosomal protein L3; HIV-1 TAR RNA-binding protein B; TARBP-B; RPL3]

other names :

[60S ribosomal protein L3 isoform a; 60S ribosomal protein L3; 60S ribosomal protein L3; ribosomal protein L3; HIV-1 TAR RNA-binding protein B; TARBP-B]

products gene name :

[RPL3]

other gene names :

[RPL3; RPL3; L3; ASC-1; TARBP-B; TARBP-B]

uniprot entry name :

RL3_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

clone :

[RB33092]

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Bovine, Monkey, Mouse, Pig, Rat, Yeast)

sequence positions :

[224-251]

sequence length :

403

specificity :

This RPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the Central region of human RPL3.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), ELISA

app notes :

WB~~1:1000. IHC-P~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Function: The L3 protein is a component of the large subunit of cytoplasmic ribosomes. Cellular Location: Nucleus, nucleolus, Cytoplasm.

products categories :

Immunology

products description :

Ribosomes, the complexes that catalyze protein synthesis consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].

products references :

Russo, A., et al. Biochim. Biophys. Acta 1799 (5-6), 419-428 (2010) :. Rikova, K., et al. Cell 131(6):1190-1203(2007). Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :. Bergqvist, M., et al. Dis. Esophagus 19(1):20-23(2006)

ncbi gi num :

4506649

ncbi acc num :

NP_000958.1

ncbi gb acc num :

NM_000967.3

uniprot acc num :

P39023

ncbi mol weight :

46109

ncbi summary :

Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

uniprot summary :

RPL3: The L3 protein is a component of the large subunit of cytoplasmic ribosomes. Belongs to the ribosomal protein L3P family. Protein type: Translation; Ribosomal; Nucleolus. Chromosomal Location of Human Ortholog: 22q13. Cellular Component: nucleoplasm; focal adhesion; cytoplasm; nucleolus; cytosol; nucleus. Molecular Function: structural constituent of ribosome; RNA binding. Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; viral reproduction; translation; translational initiation; mRNA catabolic process, nonsense-mediated decay; viral transcription; gene expression; viral infectious cycle; translational termination

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage