product summary
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company name :
MyBioSource
product type :
antibody
product name :
LILRA3 Antibody (C-term)
catalog :
MBS9214174
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
LILRA3 Antibody (C-term) (MBS9214174) western blot analysis in Daudi,HL-60,Raji and Ramos. cell line lysates (35ug/lane).This demonstrates the LILRA3 antibody detected the LILRA3 protein (arrow).
product information
catalog number :
MBS9214174
products type :
Antibody
products full name :
LILRA3 Antibody (C-term)
products short name :
[LILRA3]
products name syn :
[Leukocyte immunoglobulin-like receptor subfamily A member 3; CD85 antigen-like family member E; Immunoglobulin-like transcript 6; ILT-6; Leukocyte immunoglobulin-like receptor 4; LIR-4; Monocyte inhibitory receptor HM43/HM31; CD85e; LILRA3; ILT6; LIR4]
other names :
[leukocyte immunoglobulin-like receptor subfamily A member 3 isoform 2; Leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; CD85 antigen-like family member E; Immunoglobulin-like transcript 6; ILT-6; Leukocyte immunoglobulin-like receptor 4; LIR-4; Monocyte inhibitory receptor HM43/HM31; CD_antigen: CD85e]
products gene name :
[LILRA3]
other gene names :
[LILRA3; LILRA3; HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4; ILT6; LIR4; ILT-6; LIR-4]
uniprot entry name :
LIRA3_HUMAN
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Human
sequence positions :
[350-378]
sequence length :
456
specificity :
This LILRA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human LILRA3.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
concentration :
Vial Concentration: 0.5
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB~~1:1000
image1 heading :
Western Blot (WB)
other info1 :
Function: Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS- induced TNF-alpha production by monocytes. Cellular Location: Secreted. Tissue Location: Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.
products categories :
Crown Antibodies; Immunology; Microbiology
products description :
May act as soluble receptor for class I MHC antigens.
products references :
Zhang Z., et al. Protein Sci. 13:2819-2824(2004). Arm J.P., et al. J. Immunol. 159:2342-2349(1997). Borges L., et al. J. Immunol. 159:5192-5196(1997). Norman P.J., et al. Immunogenetics 55:165-171(2003).
ncbi gi num :
289547633
ncbi acc num :
NP_001166125.1
ncbi gb acc num :
NM_001172654.2
uniprot acc num :
Q8N6C8
ncbi mol weight :
47472
ncbi pathways :
Biotin Metabolism Pathway (11026); Biotin Metabolism Pathway (11026)
ncbi summary :
This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]
uniprot summary :
LILRA3: May act as soluble receptor for class I MHC antigens. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: plasma membrane; extracellular region. Molecular Function: receptor activity; antigen binding. Biological Process: immune system process; defense response; signal transduction
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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