CD166 Antibody (N-term) | MyBioSource MBS9213892 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

CD166 Antibody (N-term)

catalog :

MBS9213892

quantity :

0.08 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9213892

products type :

Antibody

products full name :

CD166 Antibody (N-term)

products short name :

CD166

products name syn :

CD166 antigen; Activated leukocyte cell adhesion molecule; CD166; ALCAM; MEMD

other names :

CD166 antigen isoform 2; CD166 antigen; CD166 antigen; activated leukocyte cell adhesion molecule; Activated leukocyte cell adhesion molecule; CD_antigen: CD166

products gene name :

ALCAM

other gene names :

ALCAM; ALCAM; MEMD; CD166; MEMD

uniprot entry name :

CD166_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Bovine, Mouse, Rabbit, Rat)

sequence positions :

58-87

sequence length :

305

specificity :

This CD166 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human CD166.

purity :

Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

concentration :

Vial Concentration: 2

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB~~1:1000. IHC~P~~1:50~100. FC~~1:10~50

other info1 :

Antigen Type: Synthetic Peptide. Primary Accession: Q13740. Other Accession: O35112, O46651, Q61490, Q9BH13. Cellular Location: Membrane; Single-pass type I membrane protein. Tissue Location: Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines.

other info2 :

Antigen Source: HUMAN

products categories :

Immunology

products description :

CD166 is cell adhesion molecule that binds to CD6. The protein is involved in neurite extension by neurons via heterophilic and homophilic interactions. It may play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.

products references :

Kahlert,C., Br. J. Cancer 101 (3), 457-464 (2009). Kulasingam,V., Int. J. Cancer 125 (1), 9-14 (2009)

ncbi gi num :

343168770

ncbi acc num :

NP_001230209.1

ncbi gb acc num :

NM_001243280.1

uniprot acc num :

Q13740

ncbi mol weight :

65102

ncbi pathways :

Purine Ribonucleosides Degradation Pathway (214); Purine Ribonucleosides Degradation Pathway (214); Purine Ribonucleosides Degradation Pathway (214); Purine Ribonucleosides Degradation Pathway (214); Purine Ribonucleosides Degradation Pathway (214)

ncbi summary :

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]

uniprot summary :

ALCAM: Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 3q13.1. Cellular Component: focal adhesion; cell soma; axon; integral to membrane; external side of plasma membrane. Molecular Function: protein binding; receptor binding. Biological Process: axon guidance; motor axon guidance; signal transduction; cell adhesion

size1 :

0.08 mL

price1 :

155 USD

size2 :

0.4 mL

price2 :

340

more info or order :

MyBioSource product webpage