NPFF Antibody (C-term) | MyBioSource MBS9213265 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

NPFF Antibody (C-term)

catalog :

MBS9213265

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of NPFF Antibody (C-term) in 293 cell line lysates (35ug/lane).NPFF (arrow) was detected using the purified Pab.

image 2 :

NPFF Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

product information

catalog number :

MBS9213265

products type :

Antibody

products full name :

NPFF Antibody (C-term)

products short name :

[NPFF]

products name syn :

[Pro-FMRFamide-related neuropeptide FF; FMRFamide-related peptides; Neuropeptide SF; NPSF; Neuropeptide FF; NPFF; Neuropeptide AF; NPAF; NPFF]

other names :

[pro-FMRFamide-related neuropeptide FF preproprotein; Pro-FMRFamide-related neuropeptide FF; pro-FMRFamide-related neuropeptide FF; neuropeptide FF-amide peptide precursor; FMRFamide-related peptides]

products gene name :

[NPFF]

other gene names :

[NPFF; NPFF; FMRFAL; NPSF; NPFF; NPAF]

uniprot entry name :

NPFF_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Bovine, Mouse, Rat)

sequence positions :

[86-113]

sequence length :

116

specificity :

This NPFF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-113 amino acids from the C-terminal region of human NPFF.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)

app notes :

WB~~1:1000. FC~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Flow Cytometry (FC/FACS)

other info1 :

Antigen Type: Synthetic Peptide

other info2 :

Antigen Source: HUMAN. Cellular Location: Secreted

products categories :

Neuroscience

products description :

FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two active peptides with similar function.

products references :

Yang, H.Y., et al. Neuropeptides 42(1):1-18(2008). Roumy, M., et al. J. Biol. Chem. 282(11):8332-8342(2007). Anko, M.L., et al. J. Neurochem. 96(2):573-584(2006)

ncbi gi num :

4503769

ncbi acc num :

NP_003708.1

ncbi gb acc num :

NM_003717.2

uniprot acc num :

O15130

ncbi mol weight :

12440

ncbi pathways :

Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620); Valine, Leucine And Isoleucine Degradation Pathway (8620)

ncbi summary :

uniprot summary :

NPFF: Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels. Belongs to the FARP (FMRFamide related peptide) family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 12q13.13. Cellular Component: extracellular space; dendrite; extracellular region; perikaryon; nerve terminal; vesicle. Molecular Function: neuropeptide hormone activity; G-protein-coupled receptor binding; receptor binding. Biological Process: response to drug; negative regulation of heart rate; maternal process involved in pregnancy; response to morphine; negative regulation of appetite; negative regulation of insulin secretion; vasopressin secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; spinal cord development; neuropeptide signaling pathway; regulation of sensory perception of pain; regulation of excitatory postsynaptic membrane potential; positive regulation of blood pressure; acute inflammatory response to antigenic stimulus

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage